Life Science

A glutamine analog that irreversibly inhibits glutamine-dependent amidotransferases involved in nucleotide and amino acid biosynthesis (Kis = 10 and 560 &muM for anthranilate synthase and glutamate synthase, respectively) reversibly inhibits

A general competitive antagonist of mGlu receptors (KB values = 115, 88, and 77 &microM for mGlu1a, mGlu2, and mGlu4a receptors, respectively).

A general competitive antagonist of mGlu receptors (KB values = 115, 88, and 77 &microM for mGlu1a, mGlu2, and mGlu4a receptors, respectively).

A general competitive antagonist of mGlu receptors (KB values = 115, 88, and 77 &microM for mGlu1a, mGlu2, and mGlu4a receptors, respectively).

A general competitive antagonist of mGlu receptors (KB values = 115, 88, and 77 &microM for mGlu1a, mGlu2, and mGlu4a receptors, respectively).

Amsacrine is an anticancer chemotherapeutic acridine derivative that is clinically used to treat acute myelogenous leukemia (AML). Amsacrine acts as a DNA intercalator, binding AT base pairs this inhibits the activity of topoisomerase II,

Amsacrine is an anticancer chemotherapeutic acridine derivative that is clinically used to treat acute myelogenous leukemia (AML). Amsacrine acts as a DNA intercalator, binding AT base pairs this inhibits the activity of topoisomerase II,

A cell-permeable, fluorescent dye that accumulates in acidic organelles in a pH-dependent manner and is used for autophagy detection and cell cycle determination emits green fluorescence (ex. max: 502 nm ,em.

A cell-permeable, fluorescent dye that accumulates in acidic organelles in a pH-dependent manner and is used for autophagy detection and cell cycle determination emits green fluorescence (ex. max: 502 nm ,em.

A cell-permeable, fluorescent dye that accumulates in acidic organelles in a pH-dependent manner and is used for autophagy detection and cell cycle determination emits green fluorescence (ex. max: 502 nm ,em.

An analog of latanoprost (free acid) that contains a hydrogen sulfide releasing component reduces IOP better than latanoprost in a rabbit model of glaucoma.

An analog of latanoprost (free acid) that contains a hydrogen sulfide releasing component reduces IOP better than latanoprost in a rabbit model of glaucoma.