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13620-5The isopropyl ester prodrug of AL 6556, a PGD2 receptor agonist (Ki = 3.2 µM, EC50 = 0.80 µM) produces a maximum 53% drop in IOP of the ocular hypertensive monkey with a 1 µg dose given twice daily.
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13620-500The isopropyl ester prodrug of AL 6556, a PGD2 receptor agonist (Ki = 3.2 µM, EC50 = 0.80 µM) produces a maximum 53% drop in IOP of the ocular hypertensive monkey with a 1 µg dose given twice daily.
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10010470-1An analog of AL 8810 in which the C-1 carboxyl group has been modified to an N-ethyl amide analogous to Bimatoprost.
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10010470-10An analog of AL 8810 in which the C-1 carboxyl group has been modified to an N-ethyl amide analogous to Bimatoprost.
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10010470-5An analog of AL 8810 in which the C-1 carboxyl group has been modified to an N-ethyl amide analogous to Bimatoprost.
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10113-1A lipid soluble, esterified prodrug of AL 8810.
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10113-10A lipid soluble, esterified prodrug of AL 8810.
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10113-5A lipid soluble, esterified prodrug of AL 8810.
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10008370-1AL 8810 methyl ester is a lipid soluble, esterified prodrug form of AL 8810 analogous to the commonly used therapeutic intraocular PG compounds such as latanoprost and travoprost. The pharmacology of AL 8810 methyl ester has not been published.
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10008370-10AL 8810 methyl ester is a lipid soluble, esterified prodrug form of AL 8810 analogous to the commonly used therapeutic intraocular PG compounds such as latanoprost and travoprost. The pharmacology of AL 8810 methyl ester has not been published.
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10008370-5AL 8810 methyl ester is a lipid soluble, esterified prodrug form of AL 8810 analogous to the commonly used therapeutic intraocular PG compounds such as latanoprost and travoprost. The pharmacology of AL 8810 methyl ester has not been published.
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16735-1AL 8810 is an 11&beta-fluoro analog of PGF2&alpha which acts as a potent and selective antagonist at the FP receptor. AL 8810 has weak intrinsic agonist activity on FP receptor preparations in the 200-300 nM range, yet it fully antagonizes the