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20133-500An antibiotic that inhibits growth in various tumor cell lines (IC<sub>50</sub>s = 1-5 µM) by activating caspases 8 and 3.
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19929-1An orally bioavailable Smac/DIABLO mimetic and antagonist of IAPs (Kis = 66.4, 1.
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19929-10An orally bioavailable Smac/DIABLO mimetic and antagonist of IAPs (Kis = 66.4, 1.
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19929-5An orally bioavailable Smac/DIABLO mimetic and antagonist of IAPs (Kis = 66.4, 1.
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19929-500An orally bioavailable Smac/DIABLO mimetic and antagonist of IAPs (Kis = 66.4, 1.
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13160-1A selective, competitive, and highly bioavailable inhibitor of L-PGDS (Ki = 75 µM) inhibits the production of PGD2 by L-PGDS-expressing cells purified from human CSF and recombinant mouse with an IC<sub>50</sub> value of 95 µM.
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13160-10A selective, competitive, and highly bioavailable inhibitor of L-PGDS (Ki = 75 µM) inhibits the production of PGD2 by L-PGDS-expressing cells purified from human CSF and recombinant mouse with an IC<sub>50</sub> value of 95 µM.
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13160-5A selective, competitive, and highly bioavailable inhibitor of L-PGDS (Ki = 75 µM) inhibits the production of PGD2 by L-PGDS-expressing cells purified from human CSF and recombinant mouse with an IC<sub>50</sub> value of 95 µM.
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13160-50A selective, competitive, and highly bioavailable inhibitor of L-PGDS (Ki = 75 µM) inhibits the production of PGD2 by L-PGDS-expressing cells purified from human CSF and recombinant mouse with an IC<sub>50</sub> value of 95 µM.
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11496-10A broad spectrum kinase inhibitor that potently inhibits Aurora A, Aurora B, JAK2, JAK3, and c-ABL (IC50s = 3, 3, 1.2, 1.1, and 4 nM, respectively) potently (IC50 = receptor tyrosine kinases.
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11496-25A broad spectrum kinase inhibitor that potently inhibits Aurora A, Aurora B, JAK2, JAK3, and c-ABL (IC50s = 3, 3, 1.2, 1.1, and 4 nM, respectively) potently (IC50 = receptor tyrosine kinases.
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11496-5A broad spectrum kinase inhibitor that potently inhibits Aurora A, Aurora B, JAK2, JAK3, and c-ABL (IC50s = 3, 3, 1.2, 1.1, and 4 nM, respectively) potently (IC50 = receptor tyrosine kinases.