Life Science

An anthranilic acid derivative that activates the oxidized (heme-free) form of sGC (EC₅₀ = 0.5-10 &microM in purified bovine lung or crude human corpus cavernosum) by binding to the heme pocket and mimicking its function increases cGMP

An anthranilic acid derivative that activates the oxidized (heme-free) form of sGC (EC₅₀ = 0.5-10 &microM in purified bovine lung or crude human corpus cavernosum) by binding to the heme pocket and mimicking its function increases cGMP

An inhibitor of HIV-1 protease (EC50 = 2.6 nM) commonly used in vivo in combination therapy for HIV-1 infection.

An inhibitor of HIV-1 protease (EC50 = 2.6 nM) commonly used in vivo in combination therapy for HIV-1 infection.

A hybrid molecule of an H2S donor and the NSAID diclofenac that does not cause gastric damage or promote leukocyte adherence to vascular endothelium exhibits efficacy at doses of 10-50 &micromole/kg in rat.

A hybrid molecule of an H2S donor and the NSAID diclofenac that does not cause gastric damage or promote leukocyte adherence to vascular endothelium exhibits efficacy at doses of 10-50 &micromole/kg in rat.

A hybrid molecule of an H2S donor and the NSAID diclofenac that does not cause gastric damage or promote leukocyte adherence to vascular endothelium exhibits efficacy at doses of 10-50 &micromole/kg in rat.

A hybrid molecule of an H2S donor and the NSAID diclofenac that does not cause gastric damage or promote leukocyte adherence to vascular endothelium exhibits efficacy at doses of 10-50 &micromole/kg in rat.

A hybrid molecule of an H2S donor and the NSAID indomethacin that does not cause gastric damage or promote leukocyte adherence to vascular endothelium.

A hybrid molecule of an H2S donor and the NSAID indomethacin that does not cause gastric damage or promote leukocyte adherence to vascular endothelium.

A hybrid molecule of an H2S donor and the NSAID indomethacin that does not cause gastric damage or promote leukocyte adherence to vascular endothelium.

A hybrid molecule of an H2S donor and the NSAID indomethacin that does not cause gastric damage or promote leukocyte adherence to vascular endothelium.