Life Science

An HMG-CoA reductase inhibitor that is effective in treating hypercholesterolemia and certain dyslipidemias reduces the production of LDL as well as inhibiting cholesterol synthesis metabolized by CYP3A4, prodrug several metabolites that are

An HMG-CoA reductase inhibitor that is effective in treating hypercholesterolemia and certain dyslipidemias reduces the production of LDL as well as inhibiting cholesterol synthesis metabolized by CYP3A4, prodrug several metabolites that are

An HMG-CoA reductase inhibitor that is effective in treating hypercholesterolemia and certain dyslipidemias reduces the production of LDL as well as inhibiting cholesterol synthesis metabolized by CYP3A4, prodrug several metabolites that are

An antifungal antibiotic that selectively inhibits succinate dehydrogenase (complex II IC50s = 12 and 3.7 nM in nematode and mammalian mitochondria, respectively, versus IC50s &gt 100 &muM for inhibition of complex I and complex III enzymes) has

A natural heteroglucoside that blocks mitochondrial ADP/ATP translocases, inhibiting oxidative phosphorylation.

A natural heteroglucoside that blocks mitochondrial ADP/ATP translocases, inhibiting oxidative phosphorylation.

A benzylisoquinoline that acts as a neuromuscular blocking agent with slow onset and intermediate duration causes non-depolarizing block of the neuromuscular junction.

A benzylisoquinoline that acts as a neuromuscular blocking agent with slow onset and intermediate duration causes non-depolarizing block of the neuromuscular junction.

A benzylisoquinoline that acts as a neuromuscular blocking agent with slow onset and intermediate duration causes non-depolarizing block of the neuromuscular junction.

A metabolite of atrazine.

An herbicide that is effective in controlling a broad range of weeds reportedly causes cancer in certain laboratory animals, has diverse effects on the reproductive system in animals and humans, and disrupts the normal function of the endocrine

Atrial natriuretic peptide (ANP), a stimulator of particulate guanylate cyclase, has been found to protect against reoxygenation-induced hypercontracture in isolated cardiomyocytes by increasing cyclic guanosine monophosphate synthesis ANP also