Life Science

Non-selective, competitive antagonist of the muscarinic acetylcholine receptor types M1, M2, M3, M4, and M5 (pKBs range from 8.9-9.

Non-selective, competitive antagonist of the muscarinic acetylcholine receptor types M1, M2, M3, M4, and M5 (pKBs range from 8.9-9.

AUDA is an inhibitor of sEH exhibiting IC50 values of 18 and 69 nM for the mouse and human enzymes, respectively. In angiotensin-infused rats, a dose of 25 mg/l AUDA administered in drinking water decreased mean arterial blood pressure from 161

AUDA is an inhibitor of sEH exhibiting IC50 values of 18 and 69 nM for the mouse and human enzymes, respectively. In angiotensin-infused rats, a dose of 25 mg/l AUDA administered in drinking water decreased mean arterial blood pressure from 161

AUDA is an inhibitor of sEH exhibiting IC50 values of 18 and 69 nM for the mouse and human enzymes, respectively. In angiotensin-infused rats, a dose of 25 mg/l AUDA administered in drinking water decreased mean arterial blood pressure from 161

AUDA is an inhibitor of sEH exhibiting IC50 values of 18 and 69 nM for the mouse and human enzymes, respectively. In angiotensin-infused rats, a dose of 25 mg/l AUDA administered in drinking water decreased mean arterial blood pressure from 161

A gold-thiol complex with anti-inflammatory and immunosuppressive actions potently inhibits thioredoxin reductase (IC₅₀ = 0.2 &muM) blocks LPS-mediated expression of inflammatory mediators at 10-20 &muM and blocks NF-&kappaB

A gold-thiol complex with anti-inflammatory and immunosuppressive actions potently inhibits thioredoxin reductase (IC₅₀ = 0.2 &muM) blocks LPS-mediated expression of inflammatory mediators at 10-20 &muM and blocks NF-&kappaB

A coumarin derived from citrus plants with anti-inflammatory, anti-carcinogenic, anti-bacterial, neuroprotective, and hepatoprotective activities inhibits leukocyte activation and induces phase II enzymes during the initiation phase of

A coumarin derived from citrus plants with anti-inflammatory, anti-carcinogenic, anti-bacterial, neuroprotective, and hepatoprotective activities inhibits leukocyte activation and induces phase II enzymes during the initiation phase of

A natural nitroaryl-substituted polyketide that exhibits antitumor, antifungal, and insecticidal activities non-competitive inhibitor NADH:ubiquinone oxidoreductase of bovine heart, N. crassa, and E.

A natural nitroaryl-substituted polyketide that exhibits antitumor, antifungal, and insecticidal activities non-competitive inhibitor NADH:ubiquinone oxidoreductase of bovine heart, N. crassa, and E.