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17127-1An adenosine A2B receptor agonist (EC<sub>50</sub> = 3 nM for human A2B receptors) that displays selectivity over A1, A2A, and A3 receptors (EC<sub>50</sub>s = >10 µM) used to study the role of the A2B receptor in regulating inflammation
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17127-10An adenosine A2B receptor agonist (EC<sub>50</sub> = 3 nM for human A2B receptors) that displays selectivity over A1, A2A, and A3 receptors (EC<sub>50</sub>s = >10 µM) used to study the role of the A2B receptor in regulating inflammation
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17127-25An adenosine A2B receptor agonist (EC<sub>50</sub> = 3 nM for human A2B receptors) that displays selectivity over A1, A2A, and A3 receptors (EC<sub>50</sub>s = >10 µM) used to study the role of the A2B receptor in regulating inflammation
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17127-5An adenosine A2B receptor agonist (EC<sub>50</sub> = 3 nM for human A2B receptors) that displays selectivity over A1, A2A, and A3 receptors (EC<sub>50</sub>s = >10 µM) used to study the role of the A2B receptor in regulating inflammation
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10011135-1A potent and selective PDE2 inhibitor with IC50 values of 2.0 nM (bovine) and 4.7 nM (human).
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10011135-10A potent and selective PDE2 inhibitor with IC50 values of 2.0 nM (bovine) and 4.7 nM (human).
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10011135-5A potent and selective PDE2 inhibitor with IC50 values of 2.0 nM (bovine) and 4.7 nM (human).
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11423-1A cell-permeable, reversible inhibitor of Syk (Ki = 7.5 nM IC50 = 10 nM) inhibits degranulation (IC50 = 5-46 nM) and blocks cytokine release from mast cells also sensitizes MCF-7 breast cancer cells to TRAIL-mediated apoptosis.
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11423-10A cell-permeable, reversible inhibitor of Syk (Ki = 7.5 nM IC50 = 10 nM) inhibits degranulation (IC50 = 5-46 nM) and blocks cytokine release from mast cells also sensitizes MCF-7 breast cancer cells to TRAIL-mediated apoptosis.
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11423-5A cell-permeable, reversible inhibitor of Syk (Ki = 7.5 nM IC50 = 10 nM) inhibits degranulation (IC50 = 5-46 nM) and blocks cytokine release from mast cells also sensitizes MCF-7 breast cancer cells to TRAIL-mediated apoptosis.
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15297-1Stabilizes HIF from degradation in the proteasome and increases endogenous production of erythropoietin by inhibiting HIF-1&alpha prolyl hydroxylase (IC<sub>50</sub> = 0.49 µM) investigated in clinical trial for treatment of patients with
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15297-10Stabilizes HIF from degradation in the proteasome and increases endogenous production of erythropoietin by inhibiting HIF-1&alpha prolyl hydroxylase (IC<sub>50</sub> = 0.49 µM) investigated in clinical trial for treatment of patients with