Life Science

An antagonist of ER&alpha that blocks 17&beta-estradiol-induced proliferation of drug-resistant cancer cell lines at concentrations ranging from 10 to 1,000 nM drives tumor regression in mice bearing MCF-7 xenografts inhibits ER&alpha-dependent

An antagonist of ER&alpha that blocks 17&beta-estradiol-induced proliferation of drug-resistant cancer cell lines at concentrations ranging from 10 to 1,000 nM drives tumor regression in mice bearing MCF-7 xenografts inhibits ER&alpha-dependent

An antagonist of ER&alpha that blocks 17&beta-estradiol-induced proliferation of drug-resistant cancer cell lines at concentrations ranging from 10 to 1,000 nM drives tumor regression in mice bearing MCF-7 xenografts inhibits ER&alpha-dependent

A widely used synthetic antioxidant found in all types of manufactured items from foodstuff to cosmetics to rubber and paint.

A widely used synthetic antioxidant found in all types of manufactured items from foodstuff to cosmetics to rubber and paint.

A selective inhibitor of Plk1 (IC₅₀ = 0.83 nM) induces mitotic arrest and apoptosis in diverse human cancer cell lines and drives regression of human tumor xenografts in nude mice also an inhibitor of BRD4 (IC₅₀ = 25 nM).

A selective inhibitor of Plk1 (IC₅₀ = 0.83 nM) induces mitotic arrest and apoptosis in diverse human cancer cell lines and drives regression of human tumor xenografts in nude mice also an inhibitor of BRD4 (IC₅₀ = 25 nM).

A selective inhibitor of Plk1 (IC₅₀ = 0.83 nM) induces mitotic arrest and apoptosis in diverse human cancer cell lines and drives regression of human tumor xenografts in nude mice also an inhibitor of BRD4 (IC₅₀ = 25 nM).

A selective inhibitor of Plk1 (IC₅₀ = 0.83 nM) induces mitotic arrest and apoptosis in diverse human cancer cell lines and drives regression of human tumor xenografts in nude mice also an inhibitor of BRD4 (IC₅₀ = 25 nM).

A dihydropteridinone that inhibits Plk1, Plk2, and Plk3 (IC₅₀s = 0.87, 5, and 56 nM, respectively), inducing mitotic arrest and apoptosis inhibits proliferation of multiple cancer cell lines (EC₅₀s = 11-37 nM) and prevents the

A dihydropteridinone that inhibits Plk1, Plk2, and Plk3 (IC₅₀s = 0.87, 5, and 56 nM, respectively), inducing mitotic arrest and apoptosis inhibits proliferation of multiple cancer cell lines (EC₅₀s = 11-37 nM) and prevents the

A dihydropteridinone that inhibits Plk1, Plk2, and Plk3 (IC₅₀s = 0.87, 5, and 56 nM, respectively), inducing mitotic arrest and apoptosis inhibits proliferation of multiple cancer cell lines (EC₅₀s = 11-37 nM) and prevents the