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11492-50Selective and irreversible dual inhibitor of EGFR and HER2 kinase activity (IC50s = 0.5 and 14 nM, respectively) suppresses transformation in isogenic cell-based assays, inhibits survival of cancer cell lines, and at 20 mg/kg, induces tumor
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14250-100A non-steroidal antiandrogen that binds the androgen receptor (Ki = 12.5 &muM IC<sub>50</sub> = 1.2 &muM), preventing its activation and subsequent upregulation of androgen responsive genes by androgenic hormones.
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14250-250A non-steroidal antiandrogen that binds the androgen receptor (Ki = 12.5 &muM IC<sub>50</sub> = 1.2 &muM), preventing its activation and subsequent upregulation of androgen responsive genes by androgenic hormones.
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14250-50A non-steroidal antiandrogen that binds the androgen receptor (Ki = 12.5 &muM IC<sub>50</sub> = 1.2 &muM), preventing its activation and subsequent upregulation of androgen responsive genes by androgenic hormones.
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14250-500A non-steroidal antiandrogen that binds the androgen receptor (Ki = 12.5 &muM IC<sub>50</sub> = 1.2 &muM), preventing its activation and subsequent upregulation of androgen responsive genes by androgenic hormones.
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11727-100A competitive GABAA receptor antagonist that at 100 &muM blocks spontaneously opening chloride channels in the outside-out patches from the cultured cortical neurons reversibly blocks GABAA receptors on horizontal cells in the mouse retina (IC50 =
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11727-50A competitive GABAA receptor antagonist that at 100 &muM blocks spontaneously opening chloride channels in the outside-out patches from the cultured cortical neurons reversibly blocks GABAA receptors on horizontal cells in the mouse retina (IC50 =
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11727-500A competitive GABAA receptor antagonist that at 100 &muM blocks spontaneously opening chloride channels in the outside-out patches from the cultured cortical neurons reversibly blocks GABAA receptors on horizontal cells in the mouse retina (IC50 =
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13530-1Bicyclo Prostaglandin E1 (bicyclo PGE1) is a stable, base-catalyzed transformation product of the PGE1 metabolite 13,14-dihydro-15-keto PGE1. Bicyclo PGE1 is a stable, base-catalyzed transformation product of the PGE1 metabolite
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13530-5Bicyclo Prostaglandin E1 (bicyclo PGE1) is a stable, base-catalyzed transformation product of the PGE1 metabolite 13,14-dihydro-15-keto PGE1. Bicyclo PGE1 is a stable, base-catalyzed transformation product of the PGE1 metabolite
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14530-1Bicyclo PGE2 is a stable, base-catalyzed transformation product of 13,14-dihydro-15-keto PGE2. 13,14-dihydro-15-keto PGE2 itself is a metabolite of PGE2 found in human plasma at a median level of 20-25 pg/ml.
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14530-10Bicyclo PGE2 is a stable, base-catalyzed transformation product of 13,14-dihydro-15-keto PGE2. 13,14-dihydro-15-keto PGE2 itself is a metabolite of PGE2 found in human plasma at a median level of 20-25 pg/ml.