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14530-5Bicyclo PGE2 is a stable, base-catalyzed transformation product of 13,14-dihydro-15-keto PGE2. 13,14-dihydro-15-keto PGE2 itself is a metabolite of PGE2 found in human plasma at a median level of 20-25 pg/ml.
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15384-25An antibiotic produced by S. sapporonensis that inhibits Gram-negative bacteria, including E. coli, Klebsiella, Shigella, Salmonella, Citrobacter, E. cloacae, and the pathogenic group of Neisseria.
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15384-5An antibiotic produced by S. sapporonensis that inhibits Gram-negative bacteria, including E. coli, Klebsiella, Shigella, Salmonella, Citrobacter, E. cloacae, and the pathogenic group of Neisseria.
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18744-1A topically-active imidazole antifungal compound that has broad spectrum activity in vitro against dermatophytes, molds, yeasts, dimorphic fungi, and some Gram-positive bacteria a potent inhibitor of cytochrome P450 aromatase (Ki = 68 nM,
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18744-10A topically-active imidazole antifungal compound that has broad spectrum activity in vitro against dermatophytes, molds, yeasts, dimorphic fungi, and some Gram-positive bacteria a potent inhibitor of cytochrome P450 aromatase (Ki = 68 nM,
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18744-25A topically-active imidazole antifungal compound that has broad spectrum activity in vitro against dermatophytes, molds, yeasts, dimorphic fungi, and some Gram-positive bacteria a potent inhibitor of cytochrome P450 aromatase (Ki = 68 nM,
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18744-5A topically-active imidazole antifungal compound that has broad spectrum activity in vitro against dermatophytes, molds, yeasts, dimorphic fungi, and some Gram-positive bacteria a potent inhibitor of cytochrome P450 aromatase (Ki = 68 nM,
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17652-1A potent, selective, orally bioavailable inhibitor of Syk (IC<sub>50</sub> = 1 nM) blocks B cell receptor-mediated cell signaling and activation in whole blood (IC<sub>50</sub>s = 0.27 and 0.
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17652-10A potent, selective, orally bioavailable inhibitor of Syk (IC<sub>50</sub> = 1 nM) blocks B cell receptor-mediated cell signaling and activation in whole blood (IC<sub>50</sub>s = 0.27 and 0.
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17652-5A potent, selective, orally bioavailable inhibitor of Syk (IC<sub>50</sub> = 1 nM) blocks B cell receptor-mediated cell signaling and activation in whole blood (IC<sub>50</sub>s = 0.27 and 0.
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17652-500A potent, selective, orally bioavailable inhibitor of Syk (IC<sub>50</sub> = 1 nM) blocks B cell receptor-mediated cell signaling and activation in whole blood (IC<sub>50</sub>s = 0.27 and 0.
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18269-1A potent, orally-available inhibitor of Hsp90 (Ki = 1.7 nM) that induces the degradation of oncoproteins, including HER2 (EC<sub>50</sub> = 38 nM), while up-regulating the expression of Hsp70 and Hsp27 cytotoxic to cancer cells and, when