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11072-1A protein kinase C inhibitor with structural similarity to staurosporine inhibits PKC&alpha (93% kinase activity inhibited at 1 &muM ), PDK1 (IC50 =3.8 &muM), S6K1, MAPKAP-K1, RSK2 and MSK1.
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11072-5A protein kinase C inhibitor with structural similarity to staurosporine inhibits PKC&alpha (93% kinase activity inhibited at 1 &muM ), PDK1 (IC50 =3.8 &muM), S6K1, MAPKAP-K1, RSK2 and MSK1.
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13299-1A cell permeable inhibitor of PKC with IC<sub>50</sub> values reported to range from 0.10 to 0.
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13299-10A cell permeable inhibitor of PKC with IC<sub>50</sub> values reported to range from 0.10 to 0.
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13299-25A cell permeable inhibitor of PKC with IC<sub>50</sub> values reported to range from 0.10 to 0.
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13299-5A cell permeable inhibitor of PKC with IC<sub>50</sub> values reported to range from 0.10 to 0.
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13334-1A potent, cell-permeable inhibitor of PKC isoforms (IC<sub>50</sub> = 5, 24, 14, 27, and 24 nM for PKC-&alpha, PKC-&betaI, PKC-&betaII, PKC-&gamma, and PKC-&epsilon, respectively).
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13334-10A potent, cell-permeable inhibitor of PKC isoforms (IC<sub>50</sub> = 5, 24, 14, 27, and 24 nM for PKC-&alpha, PKC-&betaI, PKC-&betaII, PKC-&gamma, and PKC-&epsilon, respectively).
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13334-5A potent, cell-permeable inhibitor of PKC isoforms (IC<sub>50</sub> = 5, 24, 14, 27, and 24 nM for PKC-&alpha, PKC-&betaI, PKC-&betaII, PKC-&gamma, and PKC-&epsilon, respectively).
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13300-1A weak inhibitor of PKC demonstrating an IC<sub>50</sub> value >100 µM blocks the activation of mitogen-stimulated protein kinase p70s6k/p85s6k (S6K) in vivo with an IC<sub>50</sub> value of 8 µM.
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13300-10A weak inhibitor of PKC demonstrating an IC<sub>50</sub> value >100 µM blocks the activation of mitogen-stimulated protein kinase p70s6k/p85s6k (S6K) in vivo with an IC<sub>50</sub> value of 8 µM.
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13300-25A weak inhibitor of PKC demonstrating an IC<sub>50</sub> value >100 µM blocks the activation of mitogen-stimulated protein kinase p70s6k/p85s6k (S6K) in vivo with an IC<sub>50</sub> value of 8 µM.