Life Science

An orally available PARP1 and PARP2 inhibitor (Kis = 1.2 and 0.85 nM, respectively) selectively targets tumor cells with BRCA1, BRCA2, or PTEN gene mutations and elicits antitumor activity in xenografted tumors.

An orally available PARP1 and PARP2 inhibitor (Kis = 1.2 and 0.85 nM, respectively) selectively targets tumor cells with BRCA1, BRCA2, or PTEN gene mutations and elicits antitumor activity in xenografted tumors.

Human Bone Morphogenetic Protein-2 (BMP-2) is a bone-growth regulatory factor and belongs to the transforming growth factor-beta (TGF-beta) superfamily. Human Bone Morphogenetic Protein-2 (BMP-2) is synthesized as large precursor molecule (Met 1

Human Bone Morphogenetic Protein-2 (BMP-2) is a bone-growth regulatory factor and belongs to the transforming growth factor-beta (TGF-beta) superfamily. Human Bone Morphogenetic Protein-2 (BMP-2) is synthesized as large precursor molecule (Met 1

Human Bone Morphogenetic Protein-2 (BMP-2) is a bone-growth regulatory factor and belongs to the transforming growth factor-beta (TGF-beta) superfamily. Human Bone Morphogenetic Protein-2 (BMP-2) is synthesized as large precursor molecule (Met 1

Human BMP-4 is one of at least 15 structurally and functionally related BMPs, which are members of the transforming growth factor ß (TGF-ß) superfamily. BMPs were originally identified as protein regulators of cartilage and bone formation.

Human BMP-4 is one of at least 15 structurally and functionally related BMPs, which are members of the transforming growth factor ß (TGF-ß) superfamily. BMPs were originally identified as protein regulators of cartilage and bone formation.

Human BMP-7 is one of at least 15 structurally and functionally related BMPs, which are members of the transforming growth factor ß (TGF-ß) superfamily. BMPs were originally identified as protein regulators of cartilage and bone formation.

Human BMP-7 is one of at least 15 structurally and functionally related BMPs, which are members of the transforming growth factor ß (TGF-ß) superfamily. BMPs were originally identified as protein regulators of cartilage and bone formation.

A cyclic nitrone spin trap that can be used for the detection and characterization of thiyl radicals, hydroxyl radicals, and superoxide anions in vitro or in vivo.

A cyclic nitrone spin trap that can be used for the detection and characterization of thiyl radicals, hydroxyl radicals, and superoxide anions in vitro or in vivo.

A cyclic nitrone spin trap that can be used for the detection and characterization of thiyl radicals, hydroxyl radicals, and superoxide anions in vitro or in vivo.