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14434-25A bpV compound that selectivity inhibits PTEN (IC<sub>50</sub> = 31 nM) also inhibits the vascular endothelial PTP, PTP-&beta (IC<sub>50</sub> = 12.7 &muM), and PTP-1&betaB (IC<sub>50</sub> = 61 &muM) and is known to be an insulin mimetic
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14434-5A bpV compound that selectivity inhibits PTEN (IC<sub>50</sub> = 31 nM) also inhibits the vascular endothelial PTP, PTP-&beta (IC<sub>50</sub> = 12.7 &muM), and PTP-1&betaB (IC<sub>50</sub> = 61 &muM) and is known to be an insulin mimetic
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17403-1A potent, selective antagonist of ETB (IC<sub>50</sub> = 1.2 nM for blocking ET-1 binding to human Girardi heart cells) competitively antagonizes the vasoconstriction induced by an ETB-selective agonist on isolated rabbit pulmonary arteries.
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17403-500A potent, selective antagonist of ETB (IC<sub>50</sub> = 1.2 nM for blocking ET-1 binding to human Girardi heart cells) competitively antagonizes the vasoconstriction induced by an ETB-selective agonist on isolated rabbit pulmonary arteries.
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15393-10A positive allosteric modulator of the M1 mAChR dose-dependently reduces the concentration of acetylcholine required to activate M1 the effective range for potentiation is 0.1 to 100 &muM with 3 nM acetylcholine restores impairment in reversal
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15393-25A positive allosteric modulator of the M1 mAChR dose-dependently reduces the concentration of acetylcholine required to activate M1 the effective range for potentiation is 0.1 to 100 &muM with 3 nM acetylcholine restores impairment in reversal
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15393-5A positive allosteric modulator of the M1 mAChR dose-dependently reduces the concentration of acetylcholine required to activate M1 the effective range for potentiation is 0.1 to 100 &muM with 3 nM acetylcholine restores impairment in reversal
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15393-50A positive allosteric modulator of the M1 mAChR dose-dependently reduces the concentration of acetylcholine required to activate M1 the effective range for potentiation is 0.1 to 100 &muM with 3 nM acetylcholine restores impairment in reversal
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16960-1Formal Name: 6-amino-1,4-dihydro-1,3-dimethyl-4-[4-(trifluoromethyl)phenyl]-pyrano[2,3-c]pyrazole-5-carbonitrile CAS Number: 1637739-82-2 Molecular Formula: C<sub>16</sub>H<sub>13</sub>F<sub>3</sub>N<sub>4</sub>O Formula Weight: 334.3
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16960-10Formal Name: 6-amino-1,4-dihydro-1,3-dimethyl-4-[4-(trifluoromethyl)phenyl]-pyrano[2,3-c]pyrazole-5-carbonitrile CAS Number: 1637739-82-2 Molecular Formula: C<sub>16</sub>H<sub>13</sub>F<sub>3</sub>N<sub>4</sub>O Formula Weight: 334.3
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16960-25Formal Name: 6-amino-1,4-dihydro-1,3-dimethyl-4-[4-(trifluoromethyl)phenyl]-pyrano[2,3-c]pyrazole-5-carbonitrile CAS Number: 1637739-82-2 Molecular Formula: C<sub>16</sub>H<sub>13</sub>F<sub>3</sub>N<sub>4</sub>O Formula Weight: 334.3
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16960-5Formal Name: 6-amino-1,4-dihydro-1,3-dimethyl-4-[4-(trifluoromethyl)phenyl]-pyrano[2,3-c]pyrazole-5-carbonitrile CAS Number: 1637739-82-2 Molecular Formula: C<sub>16</sub>H<sub>13</sub>F<sub>3</sub>N<sub>4</sub>O Formula Weight: 334.3