Life Science

A synthetic tripeptide aldehyde that acts as a potent inhibitor of cysteine proteases including calpain I (Ki = 190 nM), calpain II (Ki = 220 nM) cathepsin B (Ki = 150 nM), and cathepsin L (Ki = 500 pM) prevents the degradation of I&kappaB&alpha

A synthetic tripeptide aldehyde that acts as a potent inhibitor of cysteine proteases including calpain I (Ki = 190 nM), calpain II (Ki = 220 nM) cathepsin B (Ki = 150 nM), and cathepsin L (Ki = 500 pM) prevents the degradation of I&kappaB&alpha

A synthetic tripeptide aldehyde that acts as a potent inhibitor of cysteine proteases including calpain I (Ki = 190 nM), calpain II (Ki = 220 nM) cathepsin B (Ki = 150 nM), and cathepsin L (Ki = 500 pM) prevents the degradation of I&kappaB&alpha

A synthetic tripeptide aldehyde that acts as a potent inhibitor of cysteine proteases including calpain I (Ki = 190 nM), calpain II (Ki = 220 nM) cathepsin B (Ki = 150 nM), and cathepsin L (Ki = 500 pM) prevents the degradation of I&kappaB&alpha

A cell permeable, peptide aldehyde inhibitor of calpain I (Ki = 120 nM), calpain II (Ki = 230 nM), cathepsin B (Ki = 100 nM), and cathepsin L (Ki = 0.6 nM).

A cell permeable, peptide aldehyde inhibitor of calpain I (Ki = 120 nM), calpain II (Ki = 230 nM), cathepsin B (Ki = 100 nM), and cathepsin L (Ki = 0.6 nM).

A cell permeable, peptide aldehyde inhibitor of calpain I (Ki = 120 nM), calpain II (Ki = 230 nM), cathepsin B (Ki = 100 nM), and cathepsin L (Ki = 0.6 nM).

A cell permeable, peptide aldehyde inhibitor of calpain I (Ki = 120 nM), calpain II (Ki = 230 nM), cathepsin B (Ki = 100 nM), and cathepsin L (Ki = 0.6 nM).

A cell permeable, selective inhibitor of &mu-calpain (calpain-1) and m-calpain (calpain-2) crosses the blood-brain barrier to inhibit brain cysteine protease activity reported to have protective effects in numerous rodent models of neurotrauma

A cell permeable, selective inhibitor of &mu-calpain (calpain-1) and m-calpain (calpain-2) crosses the blood-brain barrier to inhibit brain cysteine protease activity reported to have protective effects in numerous rodent models of neurotrauma

A cell permeable, selective inhibitor of &mu-calpain (calpain-1) and m-calpain (calpain-2) crosses the blood-brain barrier to inhibit brain cysteine protease activity reported to have protective effects in numerous rodent models of neurotrauma

A cell permeable, selective inhibitor of &mu-calpain (calpain-1) and m-calpain (calpain-2) crosses the blood-brain barrier to inhibit brain cysteine protease activity reported to have protective effects in numerous rodent models of neurotrauma