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10005067-1A selective inhibitor of the 20-HETE synthase, CYP4A11, exhibiting an IC50 values of 8.8 nM when tested in human renal microsomes.
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10005067-10A selective inhibitor of the 20-HETE synthase, CYP4A11, exhibiting an IC50 values of 8.8 nM when tested in human renal microsomes.
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10005067-5A selective inhibitor of the 20-HETE synthase, CYP4A11, exhibiting an IC50 values of 8.8 nM when tested in human renal microsomes.
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10005067-50A selective inhibitor of the 20-HETE synthase, CYP4A11, exhibiting an IC50 values of 8.8 nM when tested in human renal microsomes.
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10005102-1A selective, potent inhibitor of rat FAAH (Ki = 0.57 nM) exhibited IC50 values of 0.81, 83 nM, and 50 µM for FAAH, TGH, and an uncharacterized hydrolase (KIAA1363), respectively, when screened against the serine hydrolase family of enzymes.
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10005102-10A selective, potent inhibitor of rat FAAH (Ki = 0.57 nM) exhibited IC50 values of 0.81, 83 nM, and 50 µM for FAAH, TGH, and an uncharacterized hydrolase (KIAA1363), respectively, when screened against the serine hydrolase family of enzymes.
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10005102-5A selective, potent inhibitor of rat FAAH (Ki = 0.57 nM) exhibited IC50 values of 0.81, 83 nM, and 50 µM for FAAH, TGH, and an uncharacterized hydrolase (KIAA1363), respectively, when screened against the serine hydrolase family of enzymes.
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10005102-500A selective, potent inhibitor of rat FAAH (Ki = 0.57 nM) exhibited IC50 values of 0.81, 83 nM, and 50 µM for FAAH, TGH, and an uncharacterized hydrolase (KIAA1363), respectively, when screened against the serine hydrolase family of enzymes.
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10005186-10A potent antagonist for the human IP (prostacyclin) receptor that antagonizes the carbaprostacyclin-induced activation of human neuroblastoma adenylate cyclase, blocking cAMP accumulation in a dose-dependent manner inhibits the binding of tritiated
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10005186-25A potent antagonist for the human IP (prostacyclin) receptor that antagonizes the carbaprostacyclin-induced activation of human neuroblastoma adenylate cyclase, blocking cAMP accumulation in a dose-dependent manner inhibits the binding of tritiated
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10005186-5A potent antagonist for the human IP (prostacyclin) receptor that antagonizes the carbaprostacyclin-induced activation of human neuroblastoma adenylate cyclase, blocking cAMP accumulation in a dose-dependent manner inhibits the binding of tritiated
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10004177-10A pro-apoptotic activator of the apoptosome activates caspase-3 (EC50 = 5 µM) in a cell free, multi-component assay.