-
10008657-500CAY10502 is a potent inhibitor of cPLA2&alpha with an IC50 value of 4.3 nM for the purified enzyme from human platelets.
-
10008872-1A proapoptotic, antiproliferative compound that is able to arrest cell cycle progression in the G0-G1 phase inhibits the growth of HL60, multidrug resistant HL60R, and K562 cells with IC50 values of 7.0, 23, and 20 µM, respectively.
-
10008872-10A proapoptotic, antiproliferative compound that is able to arrest cell cycle progression in the G0-G1 phase inhibits the growth of HL60, multidrug resistant HL60R, and K562 cells with IC50 values of 7.0, 23, and 20 µM, respectively.
-
10008872-5A proapoptotic, antiproliferative compound that is able to arrest cell cycle progression in the G0-G1 phase inhibits the growth of HL60, multidrug resistant HL60R, and K562 cells with IC50 values of 7.0, 23, and 20 µM, respectively.
-
10008872-50A proapoptotic, antiproliferative compound that is able to arrest cell cycle progression in the G0-G1 phase inhibits the growth of HL60, multidrug resistant HL60R, and K562 cells with IC50 values of 7.0, 23, and 20 µM, respectively.
-
10009078-10A potent inhibitor of PI3K&gamma, selectively inhibiting the &gamma isoform (IC50 = 30 nM) better than the &alpha, &beta, and &delta isoforms (IC50 = 0.94, 20, and 20 &muM, respectively) inhibits phosphorylation of PKB/Akt in mouse
-
10009078-25A potent inhibitor of PI3K&gamma, selectively inhibiting the &gamma isoform (IC50 = 30 nM) better than the &alpha, &beta, and &delta isoforms (IC50 = 0.94, 20, and 20 &muM, respectively) inhibits phosphorylation of PKB/Akt in mouse
-
10009078-5A potent inhibitor of PI3K&gamma, selectively inhibiting the &gamma isoform (IC50 = 30 nM) better than the &alpha, &beta, and &delta isoforms (IC50 = 0.94, 20, and 20 &muM, respectively) inhibits phosphorylation of PKB/Akt in mouse
-
10009078-50A potent inhibitor of PI3K&gamma, selectively inhibiting the &gamma isoform (IC50 = 30 nM) better than the &alpha, &beta, and &delta isoforms (IC50 = 0.94, 20, and 20 &muM, respectively) inhibits phosphorylation of PKB/Akt in mouse
-
10009079-1A hybrid lipoic acid-TZD derivative that transactivates human PPAR&gamma with an EC50 value of 10 µM.
-
10009079-10A hybrid lipoic acid-TZD derivative that transactivates human PPAR&gamma with an EC50 value of 10 µM.
-
10009079-5A hybrid lipoic acid-TZD derivative that transactivates human PPAR&gamma with an EC50 value of 10 µM.