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10009168-500Derivative of PGF1&alpha containing an acetylenic fluorobenzene substituent in the lower side chain binds to the recombinant human FP receptor with an IC50 value of about 0.5 µM.
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10009536-10CAY10512 is a substituted trans-stilbene analog of resveratrol that is 100-fold more potent as measured by antioxidant activity. The IC50 value for inhibition of TNF&alpha-induced activation of NF-&kappaB by CAY10512 is 0.
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10009536-100CAY10512 is a substituted trans-stilbene analog of resveratrol that is 100-fold more potent as measured by antioxidant activity. The IC50 value for inhibition of TNF&alpha-induced activation of NF-&kappaB by CAY10512 is 0.
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10009536-50CAY10512 is a substituted trans-stilbene analog of resveratrol that is 100-fold more potent as measured by antioxidant activity. The IC50 value for inhibition of TNF&alpha-induced activation of NF-&kappaB by CAY10512 is 0.
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10009536-500CAY10512 is a substituted trans-stilbene analog of resveratrol that is 100-fold more potent as measured by antioxidant activity. The IC50 value for inhibition of TNF&alpha-induced activation of NF-&kappaB by CAY10512 is 0.
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10009017-1CAY10514 is an aromatic analog of 8(S)-HETE. It acts as a dual agonist of PPAR&alpha and PPAR&gamma with EC50 values of 0.173 and 0.642 µM, respectively.
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10009017-10CAY10514 is an aromatic analog of 8(S)-HETE. It acts as a dual agonist of PPAR&alpha and PPAR&gamma with EC50 values of 0.173 and 0.642 µM, respectively.
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10009017-5CAY10514 is an aromatic analog of 8(S)-HETE. It acts as a dual agonist of PPAR&alpha and PPAR&gamma with EC50 values of 0.173 and 0.642 µM, respectively.
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10009017-50CAY10514 is an aromatic analog of 8(S)-HETE. It acts as a dual agonist of PPAR&alpha and PPAR&gamma with EC50 values of 0.173 and 0.642 µM, respectively.
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10010088-1An inhibitor of PGE2 production through the selective modulation of mPGES-1 expression dose-dependently inhibits PGE2 production in lipopolysaccharide-stimulated RAW 264.7 cells (IC50 = 1.8 µM) without affecting COX-2 expression.
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10010088-10An inhibitor of PGE2 production through the selective modulation of mPGES-1 expression dose-dependently inhibits PGE2 production in lipopolysaccharide-stimulated RAW 264.7 cells (IC50 = 1.8 µM) without affecting COX-2 expression.
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10010088-5An inhibitor of PGE2 production through the selective modulation of mPGES-1 expression dose-dependently inhibits PGE2 production in lipopolysaccharide-stimulated RAW 264.7 cells (IC50 = 1.8 µM) without affecting COX-2 expression.