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10010396-1A TP receptor antagonist that shows ~20-fold selectivity for TP&beta (IC<sub>50</sub> = 99 nM) relative to TP&alpha (IC<sub>50 </sub>= 1,970 nM) in the inhibition of U-46619-mediated Ca2+ mobilization.
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10010396-10A TP receptor antagonist that shows ~20-fold selectivity for TP&beta (IC<sub>50</sub> = 99 nM) relative to TP&alpha (IC<sub>50 </sub>= 1,970 nM) in the inhibition of U-46619-mediated Ca2+ mobilization.
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10010396-5A TP receptor antagonist that shows ~20-fold selectivity for TP&beta (IC<sub>50</sub> = 99 nM) relative to TP&alpha (IC<sub>50 </sub>= 1,970 nM) in the inhibition of U-46619-mediated Ca2+ mobilization.
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10010396-50A TP receptor antagonist that shows ~20-fold selectivity for TP&beta (IC<sub>50</sub> = 99 nM) relative to TP&alpha (IC<sub>50 </sub>= 1,970 nM) in the inhibition of U-46619-mediated Ca2+ mobilization.
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10010740-1A potent antiprion compound that inhibits the accumulation of PrPc with an IC50 value of 3 nM in both ScN2a and F3 prion-infected mouse neuroblastoma cell lines also inhibits the formation of hydroxyl radicals in vitro with an IC50 value of 90
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10010740-10A potent antiprion compound that inhibits the accumulation of PrPc with an IC50 value of 3 nM in both ScN2a and F3 prion-infected mouse neuroblastoma cell lines also inhibits the formation of hydroxyl radicals in vitro with an IC50 value of 90
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10010740-25A potent antiprion compound that inhibits the accumulation of PrPc with an IC50 value of 3 nM in both ScN2a and F3 prion-infected mouse neuroblastoma cell lines also inhibits the formation of hydroxyl radicals in vitro with an IC50 value of 90
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10010740-5A potent antiprion compound that inhibits the accumulation of PrPc with an IC50 value of 3 nM in both ScN2a and F3 prion-infected mouse neuroblastoma cell lines also inhibits the formation of hydroxyl radicals in vitro with an IC50 value of 90
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10010301-10A potent inhibitor of Cdk5 and Cdk2, with IC50 values of 64 and 98 nM, respectively.
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10010301-25A potent inhibitor of Cdk5 and Cdk2, with IC50 values of 64 and 98 nM, respectively.
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10010301-5A potent inhibitor of Cdk5 and Cdk2, with IC50 values of 64 and 98 nM, respectively.
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10010301-50A potent inhibitor of Cdk5 and Cdk2, with IC50 values of 64 and 98 nM, respectively.