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13615-10An antagonist of lipid A activation of TLR4 (IC<sub>50</sub> =1.68 &muM), in a cell-based assay significantly improves survival of mice given intraperitoneal LPS.
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13615-25An antagonist of lipid A activation of TLR4 (IC<sub>50</sub> =1.68 &muM), in a cell-based assay significantly improves survival of mice given intraperitoneal LPS.
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13615-5An antagonist of lipid A activation of TLR4 (IC<sub>50</sub> =1.68 &muM), in a cell-based assay significantly improves survival of mice given intraperitoneal LPS.
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13291-1An analog of resveratrol which potently induces apoptosis in HL-60 cells (IC<sub>50 </sub>= 40 nM versus 50 µM for resveratrol) induces apoptosis (IC<sub>50</sub> = 30 nM) in HL-60R cells, a multidrug-resistant cell line derived from HL-60
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13291-10An analog of resveratrol which potently induces apoptosis in HL-60 cells (IC<sub>50 </sub>= 40 nM versus 50 µM for resveratrol) induces apoptosis (IC<sub>50</sub> = 30 nM) in HL-60R cells, a multidrug-resistant cell line derived from HL-60
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13291-25An analog of resveratrol which potently induces apoptosis in HL-60 cells (IC<sub>50 </sub>= 40 nM versus 50 µM for resveratrol) induces apoptosis (IC<sub>50</sub> = 30 nM) in HL-60R cells, a multidrug-resistant cell line derived from HL-60
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13291-5An analog of resveratrol which potently induces apoptosis in HL-60 cells (IC<sub>50 </sub>= 40 nM versus 50 µM for resveratrol) induces apoptosis (IC<sub>50</sub> = 30 nM) in HL-60R cells, a multidrug-resistant cell line derived from HL-60
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13371-1A selective inhibitor of SPHK 1, a sphingosine kinase over expressed in several forms of cancer, both in vitro (IC<sub>50</sub> = 3.3 &muM) and in U937 cells overexpressing human SPHK 1 (70% inhibition at 5 &muM) has no inhibitory effect on SPHK
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13371-10A selective inhibitor of SPHK 1, a sphingosine kinase over expressed in several forms of cancer, both in vitro (IC<sub>50</sub> = 3.3 &muM) and in U937 cells overexpressing human SPHK 1 (70% inhibition at 5 &muM) has no inhibitory effect on SPHK
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13371-25A selective inhibitor of SPHK 1, a sphingosine kinase over expressed in several forms of cancer, both in vitro (IC<sub>50</sub> = 3.3 &muM) and in U937 cells overexpressing human SPHK 1 (70% inhibition at 5 &muM) has no inhibitory effect on SPHK
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13371-5A selective inhibitor of SPHK 1, a sphingosine kinase over expressed in several forms of cancer, both in vitro (IC<sub>50</sub> = 3.3 &muM) and in U937 cells overexpressing human SPHK 1 (70% inhibition at 5 &muM) has no inhibitory effect on SPHK
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13687-1A potent inhibitor of ROCK-I and ROCK-II kinases (IC<sub>50</sub>s = 6 and 4 nM, respectively).