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13687-10A potent inhibitor of ROCK-I and ROCK-II kinases (IC<sub>50</sub>s = 6 and 4 nM, respectively).
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13687-5A potent inhibitor of ROCK-I and ROCK-II kinases (IC<sub>50</sub>s = 6 and 4 nM, respectively).
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13836-1An antagonist of the interaction between survivin and the apoptosis-promoting protein Smac/DIABLO with an IC<sub>50</sub> value of 2.2 µM sensitizes cells to apoptotic stimuli.
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13836-10An antagonist of the interaction between survivin and the apoptosis-promoting protein Smac/DIABLO with an IC<sub>50</sub> value of 2.2 µM sensitizes cells to apoptotic stimuli.
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13836-5An antagonist of the interaction between survivin and the apoptosis-promoting protein Smac/DIABLO with an IC<sub>50</sub> value of 2.2 µM sensitizes cells to apoptotic stimuli.
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13838-1A potent, dual PI3K&alpha/mTOR inhibitor (IC<sub>50</sub>s = 0.9 and 0.6 nM, respectively) inhibits MDA361 (breast) and PC3 (prostate) tumor cell growth (IC<sub>50</sub>s = in vivo.
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13838-10A potent, dual PI3K&alpha/mTOR inhibitor (IC<sub>50</sub>s = 0.9 and 0.6 nM, respectively) inhibits MDA361 (breast) and PC3 (prostate) tumor cell growth (IC<sub>50</sub>s = in vivo.
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13838-25A potent, dual PI3K&alpha/mTOR inhibitor (IC<sub>50</sub>s = 0.9 and 0.6 nM, respectively) inhibits MDA361 (breast) and PC3 (prostate) tumor cell growth (IC<sub>50</sub>s = in vivo.
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13838-5A potent, dual PI3K&alpha/mTOR inhibitor (IC<sub>50</sub>s = 0.9 and 0.6 nM, respectively) inhibits MDA361 (breast) and PC3 (prostate) tumor cell growth (IC<sub>50</sub>s = in vivo.
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10562-1An alcohol related to a C32:6 very long chain fatty acid found in the retina its biological actions are unknown.
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10562-10An alcohol related to a C32:6 very long chain fatty acid found in the retina its biological actions are unknown.
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10562-5An alcohol related to a C32:6 very long chain fatty acid found in the retina its biological actions are unknown.