-
10562-500An alcohol related to a C32:6 very long chain fatty acid found in the retina its biological actions are unknown.
-
13695-1A TZD derivative that inhibits 15-PGDH activity with an IC<sub>50</sub> value of 31 nM.
-
13695-10A TZD derivative that inhibits 15-PGDH activity with an IC<sub>50</sub> value of 31 nM.
-
13695-25A TZD derivative that inhibits 15-PGDH activity with an IC<sub>50</sub> value of 31 nM.
-
13695-5A TZD derivative that inhibits 15-PGDH activity with an IC<sub>50</sub> value of 31 nM.
-
10642-1Inhibits recombinant human and mouse sEH (IC50s both = 0.4 nM) and demonstrates a 1,000-fold increase in potency compared to morphine in reducing hyperalgesia in an in vivo carrageenan-induced inflammatory pain model.
-
10642-10Inhibits recombinant human and mouse sEH (IC50s both = 0.4 nM) and demonstrates a 1,000-fold increase in potency compared to morphine in reducing hyperalgesia in an in vivo carrageenan-induced inflammatory pain model.
-
10642-5Inhibits recombinant human and mouse sEH (IC50s both = 0.4 nM) and demonstrates a 1,000-fold increase in potency compared to morphine in reducing hyperalgesia in an in vivo carrageenan-induced inflammatory pain model.
-
10791-1An aryl-benzoyl-imidazole which prevents proliferation of multidrug resistant cancer cells in vitro (IC50 = 28-63 nM) and inhibits melanoma xenograph tumor growth in vivo (10-30 mg/kg) binds to tubulin (Ki = 3.4 &muM) and prevents tubulin
-
10791-10An aryl-benzoyl-imidazole which prevents proliferation of multidrug resistant cancer cells in vitro (IC50 = 28-63 nM) and inhibits melanoma xenograph tumor growth in vivo (10-30 mg/kg) binds to tubulin (Ki = 3.4 &muM) and prevents tubulin
-
10791-5An aryl-benzoyl-imidazole which prevents proliferation of multidrug resistant cancer cells in vitro (IC50 = 28-63 nM) and inhibits melanoma xenograph tumor growth in vivo (10-30 mg/kg) binds to tubulin (Ki = 3.4 &muM) and prevents tubulin
-
9000549-1An intermediate used in the synthesis of potent DP2 receptor antagonists.