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19236-1An inhibitor of PHGDH, inhibiting serine synthesis from 3-PG in cells (IC<sub>50</sub> = 33 µM) inhibits the proliferation of cancer cells by blocking de novo serine synthesis.
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19236-10An inhibitor of PHGDH, inhibiting serine synthesis from 3-PG in cells (IC<sub>50</sub> = 33 µM) inhibits the proliferation of cancer cells by blocking de novo serine synthesis.
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19236-25An inhibitor of PHGDH, inhibiting serine synthesis from 3-PG in cells (IC<sub>50</sub> = 33 µM) inhibits the proliferation of cancer cells by blocking de novo serine synthesis.
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19236-5An inhibitor of PHGDH, inhibiting serine synthesis from 3-PG in cells (IC<sub>50</sub> = 33 µM) inhibits the proliferation of cancer cells by blocking de novo serine synthesis.
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19420-1CC-115 is a potent dual inhibitor of mTOR and DNA-PK (IC<sub>50</sub>s = 22 and 15 nM, respectively). CC-115 reduces PC3 cancer cell growth in vitro (IC<sub>50</sub> = 138 nM) and exhibits effective reduction of murine PC3 tumor xenografts
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19420-10CC-115 is a potent dual inhibitor of mTOR and DNA-PK (IC<sub>50</sub>s = 22 and 15 nM, respectively). CC-115 reduces PC3 cancer cell growth in vitro (IC<sub>50</sub> = 138 nM) and exhibits effective reduction of murine PC3 tumor xenografts
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19420-25CC-115 is a potent dual inhibitor of mTOR and DNA-PK (IC<sub>50</sub>s = 22 and 15 nM, respectively). CC-115 reduces PC3 cancer cell growth in vitro (IC<sub>50</sub> = 138 nM) and exhibits effective reduction of murine PC3 tumor xenografts
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19420-5CC-115 is a potent dual inhibitor of mTOR and DNA-PK (IC<sub>50</sub>s = 22 and 15 nM, respectively). CC-115 reduces PC3 cancer cell growth in vitro (IC<sub>50</sub> = 138 nM) and exhibits effective reduction of murine PC3 tumor xenografts
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19917-1A potent, selective inhibitor of mTOR.
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19917-10A potent, selective inhibitor of mTOR.
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19917-25A potent, selective inhibitor of mTOR.
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19917-5A potent, selective inhibitor of mTOR.