Life Science

A selective RAR&gamma agonist (Kds = 150, 1,500, and 2,750 nM for RAR&gamma, RAR&beta, and RAR&alpha receptors, respectively) demonstrates transcriptional activity at RAR&gamma with an AC₅₀ value of 1.8 nM.

CD19 is a 95 kDa coreceptor, which amplifies the signaling cascade in B cells. On the B cell surface, CD19 associates with CD21, CD81 and Leu-13 to exert its function.

CD19 is a 95 kDa coreceptor, which amplifies the signaling cascade in B cells. On the B cell surface, CD19 associates with CD21, CD81 and Leu-13 to exert its function.

The IL-2 receptor system consists of three non-covalently linked subunits termed IL-2Ra, IL- 2Rß, and IL-2R?. The IL-2Ra is a type I transmembrane protein consisting of a 219 amino acid (a.

The IL-2 receptor system consists of three non-covalently linked subunits termed IL-2Ra, IL- 2Rß, and IL-2R?. The IL-2Ra is a type I transmembrane protein consisting of a 219 amino acid (a.

A selective RAR&beta and RAR&gamma antagonist (Kds = 110, 306, and &gt 2,250 nM for RAR&gamma, RAR&beta, and RAR&alpha, respectively, with no binding at RXR&alpha).

A selective RAR&beta and RAR&gamma antagonist (Kds = 110, 306, and &gt 2,250 nM for RAR&gamma, RAR&beta, and RAR&alpha, respectively, with no binding at RXR&alpha).

A selective RAR&beta and RAR&gamma antagonist (Kds = 110, 306, and &gt 2,250 nM for RAR&gamma, RAR&beta, and RAR&alpha, respectively, with no binding at RXR&alpha).

Human CD28 is composed of four exons encoding a protein of 220 amino acids that is expressed on the cell surface as a glycosylated, disulfide-linked homodimer of 44 kDa. Members of the CD28 family share a number of common features.

Human CD28 is composed of four exons encoding a protein of 220 amino acids that is expressed on the cell surface as a glycosylated, disulfide-linked homodimer of 44 kDa. Members of the CD28 family share a number of common features.

CD40 Ligand (CD40L/CD154/TRAP) is a membrane glycoprotein and differentiation antigen expressed on the surface of T-cells. The CD40 ligand stimulates B-cell proliferation and secretion of all immunoglobulin isotypes in the presence of cytokines.

CD40 Ligand (CD40L/CD154/TRAP) is a membrane glycoprotein and differentiation antigen expressed on the surface of T-cells. The CD40 ligand stimulates B-cell proliferation and secretion of all immunoglobulin isotypes in the presence of cytokines.