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19956-10A selective inhibitor of TAF1 bromodomain 2 (Kd = 1.8 µM IC<sub>50</sub> = 0.9 µM) synergizes with (+)-JQ1 to inhibit the proliferation of THP-1 and H23 lung adenocarcinoma cells.
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19956-5A selective inhibitor of TAF1 bromodomain 2 (Kd = 1.8 µM IC<sub>50</sub> = 0.9 µM) synergizes with (+)-JQ1 to inhibit the proliferation of THP-1 and H23 lung adenocarcinoma cells.
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19956-500A selective inhibitor of TAF1 bromodomain 2 (Kd = 1.8 µM IC<sub>50</sub> = 0.9 µM) synergizes with (+)-JQ1 to inhibit the proliferation of THP-1 and H23 lung adenocarcinoma cells.
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20224-1A selective inhibitor of TAF1 bromodomain 2 (IC<sub>50</sub> = 2.1 µM) synergizes with (+)-JQ1 to inhibit the proliferation of THP-1 and H23 lung adenocarcinoma cells.
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20224-10A selective inhibitor of TAF1 bromodomain 2 (IC<sub>50</sub> = 2.1 µM) synergizes with (+)-JQ1 to inhibit the proliferation of THP-1 and H23 lung adenocarcinoma cells.
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20224-5A selective inhibitor of TAF1 bromodomain 2 (IC<sub>50</sub> = 2.1 µM) synergizes with (+)-JQ1 to inhibit the proliferation of THP-1 and H23 lung adenocarcinoma cells.
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20224-500A selective inhibitor of TAF1 bromodomain 2 (IC<sub>50</sub> = 2.1 µM) synergizes with (+)-JQ1 to inhibit the proliferation of THP-1 and H23 lung adenocarcinoma cells.
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18406-1A potent inhibitor of ALK (IC<sub>50</sub> = 1.9 nM) that induces concentration-dependent growth inhibition or cytotoxicity of ALK-positive cancer cells inhibits ALK tyrosine phosphorylation in tumor xenografts in mice for more than 12 hours
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18406-10A potent inhibitor of ALK (IC<sub>50</sub> = 1.9 nM) that induces concentration-dependent growth inhibition or cytotoxicity of ALK-positive cancer cells inhibits ALK tyrosine phosphorylation in tumor xenografts in mice for more than 12 hours
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18406-25A potent inhibitor of ALK (IC<sub>50</sub> = 1.9 nM) that induces concentration-dependent growth inhibition or cytotoxicity of ALK-positive cancer cells inhibits ALK tyrosine phosphorylation in tumor xenografts in mice for more than 12 hours
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18406-5A potent inhibitor of ALK (IC<sub>50</sub> = 1.9 nM) that induces concentration-dependent growth inhibition or cytotoxicity of ALK-positive cancer cells inhibits ALK tyrosine phosphorylation in tumor xenografts in mice for more than 12 hours
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18776-1A potent inhibitor of B-RafV600E (Kd = 14 nM in an in vitro binding assay) blocks B-RafV600E&ndashdependent phosphorylation of MEK in human melanoma A375 and colorectal cancer COLO 205 cells (IC<sub>50</sub>s = 78 and 60 nM, respectively)