Life Science

A potent inhibitor of B-RafV600E (Kd = 14 nM in an in vitro binding assay) blocks B-RafV600E&ndashdependent phosphorylation of MEK in human melanoma A375 and colorectal cancer COLO 205 cells (IC₅₀s = 78 and 60 nM, respectively)

A potent inhibitor of B-RafV600E (Kd = 14 nM in an in vitro binding assay) blocks B-RafV600E&ndashdependent phosphorylation of MEK in human melanoma A375 and colorectal cancer COLO 205 cells (IC₅₀s = 78 and 60 nM, respectively)

A potent inhibitor of B-RafV600E (Kd = 14 nM in an in vitro binding assay) blocks B-RafV600E&ndashdependent phosphorylation of MEK in human melanoma A375 and colorectal cancer COLO 205 cells (IC₅₀s = 78 and 60 nM, respectively)

A potent, orally available inhibitor of JAK2 (IC₅₀ = 1.3 nM) reduces the production of inflammatory cytokines and blocks disease development in mouse models of lupus and arthritis induces regression of established colorectal tumors in

A potent, orally available inhibitor of JAK2 (IC₅₀ = 1.3 nM) reduces the production of inflammatory cytokines and blocks disease development in mouse models of lupus and arthritis induces regression of established colorectal tumors in

A potent, orally available inhibitor of JAK2 (IC₅₀ = 1.3 nM) reduces the production of inflammatory cytokines and blocks disease development in mouse models of lupus and arthritis induces regression of established colorectal tumors in

An internal standard for the quantification of CEP-Lysine by GC- or LC-MS.

An internal standard for the quantification of CEP-Lysine by GC- or LC-MS.

A cephalosporin antibiotic that is active against most Gram-positive cocci, including penicillinase-producing Staphylococci, and against Gram-negative bacteria such as N. gonorrhoeae, E.

A cephalosporin antibiotic that is active against most Gram-positive cocci, including penicillinase-producing Staphylococci, and against Gram-negative bacteria such as N. gonorrhoeae, E.

A cephalosporin antibiotic that is active against most Gram-positive cocci, including penicillinase-producing Staphylococci, and against Gram-negative bacteria such as N. gonorrhoeae, E.

A cephalosporin antibiotic that is active against most Gram-positive cocci, including penicillinase-producing Staphylococci, and against Gram-negative bacteria such as N. gonorrhoeae, E.