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15035-50An anti-thrombotic agent which inhibits ADP-dependent platelet aggregation by selective and specific inhibition of cyclic nucleotide PDE3 (IC<sub>50</sub> = 200 nM).
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15613-10A potent agonist of &beta-adrenergic receptors (pEC<sub>50</sub> = 8.13, 8.78, and 6.62 for human &beta1, &beta2, and &beta3, respectively).
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15613-50A potent agonist of &beta-adrenergic receptors (pEC<sub>50</sub> = 8.13, 8.78, and 6.62 for human &beta1, &beta2, and &beta3, respectively).
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18743-10An H2 receptor antagonist (Ki = 0.6 µM) that competitively inhibits the binding of histamine to H2 receptors, thereby reducing both intracellular cAMP concentrations and acid secretion by parietal cells.
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18743-25An H2 receptor antagonist (Ki = 0.6 µM) that competitively inhibits the binding of histamine to H2 receptors, thereby reducing both intracellular cAMP concentrations and acid secretion by parietal cells.
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18743-5An H2 receptor antagonist (Ki = 0.6 µM) that competitively inhibits the binding of histamine to H2 receptors, thereby reducing both intracellular cAMP concentrations and acid secretion by parietal cells.
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18743-50An H2 receptor antagonist (Ki = 0.6 µM) that competitively inhibits the binding of histamine to H2 receptors, thereby reducing both intracellular cAMP concentrations and acid secretion by parietal cells.
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16042-10A calcimimetic that allosterically activates the calcium-sensing receptor (CaSR pEC<sub>50</sub> = 7.3 in HEK293T cells expressing CaSR) inhibiting parathyroid hormone secretion.
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16042-100A calcimimetic that allosterically activates the calcium-sensing receptor (CaSR pEC<sub>50</sub> = 7.3 in HEK293T cells expressing CaSR) inhibiting parathyroid hormone secretion.
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16042-25A calcimimetic that allosterically activates the calcium-sensing receptor (CaSR pEC<sub>50</sub> = 7.3 in HEK293T cells expressing CaSR) inhibiting parathyroid hormone secretion.
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16042-50A calcimimetic that allosterically activates the calcium-sensing receptor (CaSR pEC<sub>50</sub> = 7.3 in HEK293T cells expressing CaSR) inhibiting parathyroid hormone secretion.
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17468-1An activator of sGC that binds to a regulatory site, resulting in activation in an NO-independent manner (Kd = 3.2 nM) reduces hypertension, limits cardiomyocyte hypertrophy, protects against ischemia/reperfusion injury, and reduces morbidity and