Life Science

An aminopyrimidine that binds a range of tyrosine kinases, including ABL, BTK, FAK, FER, JAK1, SRC, SYK, TEC, TNK1, TYK2, and YES.

A cell-permeant inhibitor of CK1 (IC₅₀ = 200 nM from S. pombe, 300 nM for CK1&delta) only weakly affects the activities of a panel of kinases tested.

A cell-permeant inhibitor of CK1 (IC₅₀ = 200 nM from S. pombe, 300 nM for CK1&delta) only weakly affects the activities of a panel of kinases tested.

A cell-permeant inhibitor of CK1 (IC₅₀ = 200 nM from S. pombe, 300 nM for CK1&delta) only weakly affects the activities of a panel of kinases tested.

A cell-permeant inhibitor of CK1 (IC₅₀ = 200 nM from S. pombe, 300 nM for CK1&delta) only weakly affects the activities of a panel of kinases tested.

TRPA1 channel agonist and xanthine oxidase inhibitor. It increases levels of phase II enzymes in models of colon carcinogenesis and suppresses tumor growth in animal models of squamous cell carcinoma.

TRPA1 channel agonist and xanthine oxidase inhibitor. It increases levels of phase II enzymes in models of colon carcinogenesis and suppresses tumor growth in animal models of squamous cell carcinoma.

TRPA1 channel agonist and xanthine oxidase inhibitor. It increases levels of phase II enzymes in models of colon carcinogenesis and suppresses tumor growth in animal models of squamous cell carcinoma.

A natural inhibitor of exportin 1, preventing the export of proteins from the nucleus reduces several intracellular signaling pathways, including NF-&kappaB, impacting inflammation, cancer, viral replication, and other processes.

A natural inhibitor of exportin 1, preventing the export of proteins from the nucleus reduces several intracellular signaling pathways, including NF-&kappaB, impacting inflammation, cancer, viral replication, and other processes.

A natural inhibitor of exportin 1, preventing the export of proteins from the nucleus reduces several intracellular signaling pathways, including NF-&kappaB, impacting inflammation, cancer, viral replication, and other processes.

A natural inhibitor of exportin 1, preventing the export of proteins from the nucleus reduces several intracellular signaling pathways, including NF-&kappaB, impacting inflammation, cancer, viral replication, and other processes.