Life Science

The phosphatidylinositol 3-kinase (PI3K)/Akt signal transduction pathway plays critical roles in cell growth and proliferation making it an attractive target for anticancer agents. Ins(1,3,4,5,6)P5 is one of the many inositol phosphate isomers that

The phosphatidylinositol 3-kinase (PI3K)/Akt signal transduction pathway plays critical roles in cell growth and proliferation making it an attractive target for anticancer agents. Ins(1,3,4,5,6)P5 is one of the many inositol phosphate isomers that

D-myo-Inositol-1,3,4,5-tetraphosphate (Ins(1,3,4,5)-P4) is formed by the phosphorylation of Ins(1,4,5)P3 by inositol 1,4,5-triphosphate 3-kinase. Ins(1,3,4,5)-P4 increases intracellular calcium levels by two distinct mechanisms: opening calcium

D-myo-Inositol-1,3,4,5-tetraphosphate (Ins(1,3,4,5)-P4) is formed by the phosphorylation of Ins(1,4,5)P3 by inositol 1,4,5-triphosphate 3-kinase. Ins(1,3,4,5)-P4 increases intracellular calcium levels by two distinct mechanisms: opening calcium

D-myo-Inositol-1,3,4,5-tetraphosphate (Ins(1,3,4,5)-P4) is formed by the phosphorylation of Ins(1,4,5)P3 by inositol 1,4,5-triphosphate 3-kinase. Ins(1,3,4,5)-P4 increases intracellular calcium levels by two distinct mechanisms: opening calcium

Largely acts a cell signaling intermediate serving as substrate to produce IP5s, which can be further phosphorylated to produce Ins(1,2,3,4,5,6-)P6 also phosphorylated to produce phytic acid, which serves diverse roles in eukaryotic tissues a

Largely acts a cell signaling intermediate serving as substrate to produce IP5s, which can be further phosphorylated to produce Ins(1,2,3,4,5,6-)P6 also phosphorylated to produce phytic acid, which serves diverse roles in eukaryotic tissues a

Largely acts a cell signaling intermediate serving as substrate to produce IP5s, which can be further phosphorylated to produce Ins(1,2,3,4,5,6-)P6 also phosphorylated to produce phytic acid, which serves diverse roles in eukaryotic tissues a

A member of the InsP family of small, soluble second messengers inhibits Ins(3,4,5,6)P4 kinase activity to increase the cellular level of Ins(3,4,5,6)P4.

A member of the InsP family of small, soluble second messengers inhibits Ins(3,4,5,6)P4 kinase activity to increase the cellular level of Ins(3,4,5,6)P4.

A member of the InsP family of small, soluble second messengers inhibits Ins(3,4,5,6)P4 kinase activity to increase the cellular level of Ins(3,4,5,6)P4.

Ins(1,3,5)P3 is a member of the inositol phosphate (InsP) family of second messengers that play a critical role in the transmission of cellular signals. The most studied InsP, Ins(1,4,5)P3 is a second messenger produced in cells by PLC-mediated