Life Science

Danusertib is a pan-Aurora kinase inhibitor (IC₅₀s = 13, 79, and 61 nM for Aurora A, B, and C, respectively) that also targets Abl, Ret, TrkA and FGFR1 (IC₅₀s = 25, 31, 31, and 47 nM, respectively). It exhibits

Danusertib is a pan-Aurora kinase inhibitor (IC₅₀s = 13, 79, and 61 nM for Aurora A, B, and C, respectively) that also targets Abl, Ret, TrkA and FGFR1 (IC₅₀s = 25, 31, 31, and 47 nM, respectively). It exhibits

Danusertib is a pan-Aurora kinase inhibitor (IC₅₀s = 13, 79, and 61 nM for Aurora A, B, and C, respectively) that also targets Abl, Ret, TrkA and FGFR1 (IC₅₀s = 25, 31, 31, and 47 nM, respectively). It exhibits

Danusertib is a pan-Aurora kinase inhibitor (IC₅₀s = 13, 79, and 61 nM for Aurora A, B, and C, respectively) that also targets Abl, Ret, TrkA and FGFR1 (IC₅₀s = 25, 31, 31, and 47 nM, respectively). It exhibits

A first generation, selective SGLT inhibitor that blocks glucose transport with about 100-fold selectivity for SGLT2 (Ki = 6 nM EC50 = 1.1 nM) over SGLT1 (Ki = 390 nM) 0.

A first generation, selective SGLT inhibitor that blocks glucose transport with about 100-fold selectivity for SGLT2 (Ki = 6 nM EC50 = 1.1 nM) over SGLT1 (Ki = 390 nM) 0.

A first generation, selective SGLT inhibitor that blocks glucose transport with about 100-fold selectivity for SGLT2 (Ki = 6 nM EC50 = 1.1 nM) over SGLT1 (Ki = 390 nM) 0.

A first generation, selective SGLT inhibitor that blocks glucose transport with about 100-fold selectivity for SGLT2 (Ki = 6 nM EC50 = 1.1 nM) over SGLT1 (Ki = 390 nM) 0.

A fluorescent probe which is commonly used to stain DNA and chromosomes for fluorescent microscopy and flow cytometry applications characterized by ultraviolet (max 358 nm) excitation and blue (max 461 nm) emission wavelengths.

A fluorescent probe which is commonly used to stain DNA and chromosomes for fluorescent microscopy and flow cytometry applications characterized by ultraviolet (max 358 nm) excitation and blue (max 461 nm) emission wavelengths.

A fluorescent probe which is commonly used to stain DNA and chromosomes for fluorescent microscopy and flow cytometry applications characterized by ultraviolet (max 358 nm) excitation and blue (max 461 nm) emission wavelengths.

Non-nucleoside reverse transcriptase inhibitors (NNRTIs) are highly specific and potent allosteric inhibitors of HIV-1 reverse transcriptase. Dapivirine, a diarylpyrimidine derivative of the potent NNRTI efavirenz (Item No.