Life Science

Non-nucleoside reverse transcriptase inhibitors (NNRTIs) are highly specific and potent allosteric inhibitors of HIV-1 reverse transcriptase. Dapivirine, a diarylpyrimidine derivative of the potent NNRTI efavirenz (Item No.

Non-nucleoside reverse transcriptase inhibitors (NNRTIs) are highly specific and potent allosteric inhibitors of HIV-1 reverse transcriptase. Dapivirine, a diarylpyrimidine derivative of the potent NNRTI efavirenz (Item No.

Non-nucleoside reverse transcriptase inhibitors (NNRTIs) are highly specific and potent allosteric inhibitors of HIV-1 reverse transcriptase. Dapivirine, a diarylpyrimidine derivative of the potent NNRTI efavirenz (Item No.

An orally bioavailable inhibitor of HIF prolyl hydroxylase that increases HIF stability and action induces an effective EPO response and stimulates non-EPO mechanisms of erythropoiesis.

An orally bioavailable inhibitor of HIF prolyl hydroxylase that increases HIF stability and action induces an effective EPO response and stimulates non-EPO mechanisms of erythropoiesis.

An orally bioavailable inhibitor of HIF prolyl hydroxylase that increases HIF stability and action induces an effective EPO response and stimulates non-EPO mechanisms of erythropoiesis.

An orally bioavailable inhibitor of HIF prolyl hydroxylase that increases HIF stability and action induces an effective EPO response and stimulates non-EPO mechanisms of erythropoiesis.

An inhibitor of &gamma-secretase, blocking the production of total A&beta in human primary neuronal cultures with an IC₅₀ value of 115 nM and A&beta42 with an IC₅₀ value of 200 nM reduces brain levels of A&beta in vivo

An inhibitor of &gamma-secretase, blocking the production of total A&beta in human primary neuronal cultures with an IC₅₀ value of 115 nM and A&beta42 with an IC₅₀ value of 200 nM reduces brain levels of A&beta in vivo

An inhibitor of &gamma-secretase, blocking the production of total A&beta in human primary neuronal cultures with an IC₅₀ value of 115 nM and A&beta42 with an IC₅₀ value of 200 nM reduces brain levels of A&beta in vivo

An inhibitor of &gamma-secretase, blocking the production of total A&beta in human primary neuronal cultures with an IC₅₀ value of 115 nM and A&beta42 with an IC₅₀ value of 200 nM reduces brain levels of A&beta in vivo

A lipopeptide antibiotic effective against resistant Gram-positive bacteria (MIC90s range from 0.25-16 mg/L) alters bacterial plasma membrane potential and redirects the binding of proteins essential for cell division and cell wall synthesis.