Life Science

A selective DDR1 inhibitor (IC₅₀ = 105 nM EC₅₀ = 87 nM inhibits colorectal cancer cell lines when used in combination with the PI3K/mTOR inhibitor, GSK2126458.

A selective DDR1 inhibitor (IC₅₀ = 105 nM EC₅₀ = 87 nM inhibits colorectal cancer cell lines when used in combination with the PI3K/mTOR inhibitor, GSK2126458.

A NO donor with a half-life of 2 minutes at 37&degC, pH 7.4 liberates 1.5 moles of NO per mole of parent compound.

A NO donor with a half-life of 2 minutes at 37&degC, pH 7.4 liberates 1.5 moles of NO per mole of parent compound.

A NO donor with a half-life of 2 minutes at 37&degC, pH 7.4 liberates 1.5 moles of NO per mole of parent compound.

A NO donor with a half-life of 2 minutes at 37&degC, pH 7.4 liberates 1.5 moles of NO per mole of parent compound.

A marine sponge alkaloid that inhibits Chk1 and Chk2 (IC₅₀ = 3 and 3.5 &microM, respectively), blocking G2 arrest also inhibits MEK-1 (IC₅₀ = 881 nM), GSK3&beta (IC₅₀ = 1.

One of several nitroaniline fatty acid amides that can be used to measure FAAH activity exposure to FAAH results in the release of the yellow colorimetric dye m-nitroaniline (&epsilon = 13,500 at 410 nm) allowing for fast and convenient

One of several nitroaniline fatty acid amides that can be used to measure FAAH activity exposure to FAAH results in the release of the yellow colorimetric dye m-nitroaniline (&epsilon = 13,500 at 410 nm) allowing for fast and convenient

One of several nitroaniline fatty acid amides that can be used to measure FAAH activity exposure to FAAH results in the release of the yellow colorimetric dye m-nitroaniline (&epsilon = 13,500 at 410 nm) allowing for fast and convenient

One of several nitroaniline fatty acid amides that can be used to measure FAAH activity exposure to FAAH results in the release of the yellow colorimetric dye m-nitroaniline (&epsilon = 13,500 at 410 nm) allowing for fast and convenient

A 2&#39 deoxy analog of 5-azacytidine which is incorporated into DNA and causes hypomethylation by inhibiting DNA methyltransferases in a concentration-dependent manner useful in conditions characterized by DNA hypermethylation, as is found in