Biologically Active Small Molecules

A major green tea polyphenol with antioxidant, anti-inflammatory, and anticancer activities.

A natural neurotransmitter that is activates adrenoceptors (Kis = 15, 735, and 3,970 nM for &alpha1A-, &beta2-, and &beta1-adrenergic receptors, respectively) may induce either contraction or relaxation of vascular smooth muscle, depending on

A natural neurotransmitter that is activates adrenoceptors (Kis = 15, 735, and 3,970 nM for &alpha1A-, &beta2-, and &beta1-adrenergic receptors, respectively) may induce either contraction or relaxation of vascular smooth muscle, depending on

A natural neurotransmitter that is activates adrenoceptors (Kis = 15, 735, and 3,970 nM for &alpha1A-, &beta2-, and &beta1-adrenergic receptors, respectively) may induce either contraction or relaxation of vascular smooth muscle, depending on

An epimer of (&minus)-EGC and potent antioxidant significantly inhibits the proliferation of HCT116 and SW-480 cancer cells inhibits the aggregation of amyloid &beta peptide in vitro (IC₅₀ = 17.5 &microM).

An epimer of (&minus)-EGC and potent antioxidant significantly inhibits the proliferation of HCT116 and SW-480 cancer cells inhibits the aggregation of amyloid &beta peptide in vitro (IC₅₀ = 17.5 &microM).

An epimer of (&minus)-EGC and potent antioxidant significantly inhibits the proliferation of HCT116 and SW-480 cancer cells inhibits the aggregation of amyloid &beta peptide in vitro (IC₅₀ = 17.5 &microM).

An epimer of (&minus)-EGC and potent antioxidant significantly inhibits the proliferation of HCT116 and SW-480 cancer cells inhibits the aggregation of amyloid &beta peptide in vitro (IC₅₀ = 17.5 &microM).

A natural sesquiterpene alkaloid that inhibits AChE in rat cortex in vitro (IC₅₀ = 82 nM) and displays oral AChE inhibitory activity in animals.

A natural sesquiterpene alkaloid that inhibits AChE in rat cortex in vitro (IC₅₀ = 82 nM) and displays oral AChE inhibitory activity in animals.

A tumor-promoting teleocidin compound that activates PKC (Ki = 3.4 nM and 1 &muM for PKC&eta and PKC&gamma, respectively) induces differentiation of human embryonic stem cells into pancreatic progenitors.

The inactive stereoisomer of a selective BET bromodomain inhibitor.