Biologically Active Small Molecules

The predominant LO product of arachidonic acid formed in mammalian platelets enhances tumor cell adhesion to endothelial cells, fibronectin, and the subendothelial matrix at 0.1 &microM.

The predominant LO product of arachidonic acid formed in mammalian platelets enhances tumor cell adhesion to endothelial cells, fibronectin, and the subendothelial matrix at 0.1 &microM.

12(S)-HETE-d8 contains eight deuterium atoms at the 5, 6, 8, 9, 11, 12, 14 and 15 positions. It is intended for use as an internal standard for the quantification of 12(S)-HETE by GC- or LC-mass spectrometry (MS).

12(S)-HETE-d8 contains eight deuterium atoms at the 5, 6, 8, 9, 11, 12, 14 and 15 positions. It is intended for use as an internal standard for the quantification of 12(S)-HETE by GC- or LC-mass spectrometry (MS).

12(S)-HETE-d8 contains eight deuterium atoms at the 5, 6, 8, 9, 11, 12, 14 and 15 positions. It is intended for use as an internal standard for the quantification of 12(S)-HETE by GC- or LC-mass spectrometry (MS).

A product of 12-LO oxidation of DGLA that inhibits agonist-mediated platelet activation (IC₅₀ = 40 &microM).

A product of 12-LO oxidation of DGLA that inhibits agonist-mediated platelet activation (IC₅₀ = 40 &microM).

A product of 12-LO oxidation of DGLA that inhibits agonist-mediated platelet activation (IC₅₀ = 40 &microM).

A product of 12-LO oxidation of DGLA that inhibits agonist-mediated platelet activation (IC₅₀ = 40 &microM).

An unusual, yet primary, product of the COX pathway biosynthesized by TX synthase in the human platelet.

An unusual, yet primary, product of the COX pathway biosynthesized by TX synthase in the human platelet.

An unusual, yet primary, product of the COX pathway biosynthesized by TX synthase in the human platelet.