Biologically Active Small Molecules

A metabolically stable methyl sulfonamide analog of 14(15)-EET equipotent to 14(15)-EET in vascular agonist activity.

A metabolically stable methyl sulfonamide analog of 14(15)-EET equipotent to 14(15)-EET in vascular agonist activity.

An oxygenation product of DHA that serves as a precursor to the anti-inflammatory, pro-resolving maresin 1 doses as low as 0.2 ng/mouse resulted in reduced infiltration of PMNs into sites of inflammation.

An oxygenation product of DHA that serves as a precursor to the anti-inflammatory, pro-resolving maresin 1 doses as low as 0.2 ng/mouse resulted in reduced infiltration of PMNs into sites of inflammation.

An oxygenation product of DHA that serves as a precursor to the anti-inflammatory, pro-resolving maresin 1 doses as low as 0.2 ng/mouse resulted in reduced infiltration of PMNs into sites of inflammation.

14(Z)-Eicosenoic acid is a monounsaturated fatty acid. It is found in small quantities in marine life including the sponge (Tedania dirhaphis) and goldfish (Carassius auratus).

14(Z)-Eicosenoic acid is a monounsaturated fatty acid. It is found in small quantities in marine life including the sponge (Tedania dirhaphis) and goldfish (Carassius auratus).

14(Z)-Eicosenoic acid is a monounsaturated fatty acid. It is found in small quantities in marine life including the sponge (Tedania dirhaphis) and goldfish (Carassius auratus).

14(Z)-Eicosenoic acid is a monounsaturated fatty acid. It is found in small quantities in marine life including the sponge (Tedania dirhaphis) and goldfish (Carassius auratus).

A LTB4 receptor antagonist that has a higher binding affinity for BLT1 (Ki = 27 nM) compared to BLT2 (Ki = 473 nM) inhibits LTB4-induced release of lysozymes from rat polymorphonuclear leukoctyes with an IC₅₀ value of 1 &microM.

A LTB4 receptor antagonist that has a higher binding affinity for BLT1 (Ki = 27 nM) compared to BLT2 (Ki = 473 nM) inhibits LTB4-induced release of lysozymes from rat polymorphonuclear leukoctyes with an IC₅₀ value of 1 &microM.

A LTB4 receptor antagonist that has a higher binding affinity for BLT1 (Ki = 27 nM) compared to BLT2 (Ki = 473 nM) inhibits LTB4-induced release of lysozymes from rat polymorphonuclear leukoctyes with an IC₅₀ value of 1 &microM.