Biologically Active Small Molecules

15(R)-PGF2&alpha is the C-15 epimer of the naturally occurring mammalian autacoid PGF2&alpha. It has only 25% of the potency of PGF2&alpha in hamster antifertility studies, which may be due to reduced affinity for FP receptors.

15(R)-PGF2&alpha is the C-15 epimer of the naturally occurring mammalian autacoid PGF2&alpha. It has only 25% of the potency of PGF2&alpha in hamster antifertility studies, which may be due to reduced affinity for FP receptors.

15(R)-PGF2&alpha is the C-15 epimer of the naturally occurring mammalian autacoid PGF2&alpha. It has only 25% of the potency of PGF2&alpha in hamster antifertility studies, which may be due to reduced affinity for FP receptors.

15(S)-15-methyl PGD2 is a metabolically stable synthetic analog of PGD2. In contrast to PGD2, 15(S)-15-methyl PGD2 induces vasoconstriction and increases systemic blood pressure with much reduced inhibitory activity on ADP-induced platelet

15(S)-15-methyl PGE1 is a metabolically stable synthetic analog of PGE1. In sharp contrast to the bronchodilatory effects of PGE1, 15(S)-15-methyl PGE1 is a weak constrictor of human respiratory tract smooth muscle.

15(S)-15-methyl PGE2 is a potent, metabolically stable analog of PGE2. It is a potent gastric antisecretory and antiulcer compound.

15(S)-15-methyl PGE2 is a potent, metabolically stable analog of PGE2. It is a potent gastric antisecretory and antiulcer compound.

15(S)-15-methyl PGF2&alpha methyl ester is a derivative of 15(S)-15-methyl PGF2&alpha with increased membrane permeability. Hydrolysis of the methyl ester in vivo releases the biologically active 15(S)-15-methyl PGF2&alpha, which is a potent

15(S)-15-methyl PGF2&alpha is a metabolically stable analog of PGF2&alpha. It is a potent uterine stimulant and abortifacient which can be administered intramuscularly to induce labor.

Unnatural C-15 epimer of Travoprost.

Unnatural C-15 epimer of Travoprost.

Unnatural C-15 epimer of Travoprost.