Biologically Active Small Molecules

A minor CYP450 metabolite of arachidonic acid that potently inhibits proximal tubule ATPase activity.

An isomer of iloprost that potently inhibits platelet aggregation with an IC 50 value of 3.5 nM.

An isomer of iloprost that potently inhibits platelet aggregation with an IC 50 value of 3.5 nM.

An isomer of iloprost that potently inhibits platelet aggregation with an IC 50 value of 3.5 nM.

A metabolism resistant analog of PGA1

A metabolism resistant analog of PGA1

A metabolism resistant analog of PGA1

16,16-dimethyl PGA2 is a metabolism resistant analog of PGA2 with a prolonged in vivo half-life. It inhibits the proliferation of Sendai virus in cultured African green monkey kidney cells by &gt90% at a concentration of 4 &microg/ml.

16,16-dimethyl PGA2 is a metabolism resistant analog of PGA2 with a prolonged in vivo half-life. It inhibits the proliferation of Sendai virus in cultured African green monkey kidney cells by &gt90% at a concentration of 4 &microg/ml.

16,16-dimethyl PGA2 is a metabolism resistant analog of PGA2 with a prolonged in vivo half-life. It inhibits the proliferation of Sendai virus in cultured African green monkey kidney cells by &gt90% at a concentration of 4 &microg/ml.

16,16-dimethyl PGD2 is a metabolically stable synthetic analog of PGD2. It enhances ADP-induced human platelet aggregation and increases systemic blood pressure in rats.

16,16-dimethyl PGD2 is a metabolically stable synthetic analog of PGD2. It enhances ADP-induced human platelet aggregation and increases systemic blood pressure in rats.