Biologically Active Small Molecules

LPA is a potent lipid mediator that elicits its effect through four distinct receptors - LPA1/EDG-2, LPA2/EDG-4, LPA3/EDG-7 and LPA4/GPR23.{11049,13009} OMPT is a selective agonist of the LPA3 receptor.

LPA is a potent lipid mediator that elicits its effect through four distinct receptors - LPA1/EDG-2, LPA2/EDG-4, LPA3/EDG-7 and LPA4/GPR23.{11049,13009} OMPT is a selective agonist of the LPA3 receptor.

An enantiomer of atorvastatin that has little or no inhibitory activity against HMG-CoA reductase.

An enantiomer of atorvastatin that has little or no inhibitory activity against HMG-CoA reductase.

An enantiomer of atorvastatin that has little or no inhibitory activity against HMG-CoA reductase.

A synthetic auxin that has been used to promote hypocotyl elongation during seedling emergence.

A synthetic auxin that has been used to promote hypocotyl elongation during seedling emergence.

A synthetic auxin that has been used to promote hypocotyl elongation during seedling emergence.

A synthetic auxin that has been used to promote hypocotyl elongation during seedling emergence.

A natural resorcylic lactone derived from fungi that selectively inhibits purified TAK1 (IC₅₀ = 8.1 nM when co-expressed with the TAK1-binding protein, TAB1) irreversibly blocks IL-1-induced activation of TAK1, NF-&kappaB, and JNK/p38

A natural resorcylic lactone derived from fungi that selectively inhibits purified TAK1 (IC₅₀ = 8.1 nM when co-expressed with the TAK1-binding protein, TAB1) irreversibly blocks IL-1-induced activation of TAK1, NF-&kappaB, and JNK/p38

A stable isomer of 15(S)-HETE that elicits contraction of isolated pulmonary arteries from rabbits and inhibits the proliferation and migration of PC-3 cells.