Biologically Active Small Molecules

A synthetic analog of curcumin that activates enzymes which catalyze detoxification reactions through the Keap1-Nrf2-ARE pathway increases NQO1 activity, glutathione reductase activity, and total glutathione levels in vitro at 0.6 &ndash 0.

A synthetic analog of curcumin that activates enzymes which catalyze detoxification reactions through the Keap1-Nrf2-ARE pathway increases NQO1 activity, glutathione reductase activity, and total glutathione levels in vitro at 0.6 &ndash 0.

Inhibits HDAC activity much more potently (IC₅₀ = 13 &microM) than valproic acid (IC₅₀ = 398 &microM) induces histone hyperacetylation in cerebellar granule cells significantly at 5 &microM induces the expression of

Inhibits HDAC activity much more potently (IC₅₀ = 13 &microM) than valproic acid (IC₅₀ = 398 &microM) induces histone hyperacetylation in cerebellar granule cells significantly at 5 &microM induces the expression of

Inhibits HDAC activity much more potently (IC₅₀ = 13 &microM) than valproic acid (IC₅₀ = 398 &microM) induces histone hyperacetylation in cerebellar granule cells significantly at 5 &microM induces the expression of

Inhibits HDAC activity much more potently (IC₅₀ = 13 &microM) than valproic acid (IC₅₀ = 398 &microM) induces histone hyperacetylation in cerebellar granule cells significantly at 5 &microM induces the expression of

The major metabolite formed during the metabolism of the non-steroidal antiandrogen flutamide by cytochrome P450 isoforms CYP1A2 and CYP3A4 inhibits the binding of testosterone to the nuclear androgen receptor (IC₅₀ = ~300-900), blocking

The major metabolite formed during the metabolism of the non-steroidal antiandrogen flutamide by cytochrome P450 isoforms CYP1A2 and CYP3A4 inhibits the binding of testosterone to the nuclear androgen receptor (IC₅₀ = ~300-900), blocking

The major metabolite formed during the metabolism of the non-steroidal antiandrogen flutamide by cytochrome P450 isoforms CYP1A2 and CYP3A4 inhibits the binding of testosterone to the nuclear androgen receptor (IC₅₀ = ~300-900), blocking

The major metabolite formed during the metabolism of the non-steroidal antiandrogen flutamide by cytochrome P450 isoforms CYP1A2 and CYP3A4 inhibits the binding of testosterone to the nuclear androgen receptor (IC₅₀ = ~300-900), blocking

2-Hydroxymyristic acid is an inhibitor of protein myristoylation requiring about 0.5 mM concentration for full inhibition of acylation.

2-Hydroxymyristic acid is an inhibitor of protein myristoylation requiring about 0.5 mM concentration for full inhibition of acylation.