Biologically Active Small Molecules

A CYP450 &omega-oxidation metabolite of PGE2 that preceeds &beta-oxidation and the loss of up to four carbons from the lower side chain of PGE2.

A CYP450 &omega-oxidation metabolite of PGF2&alpha.

A CYP450 &omega-oxidation metabolite of PGF2&alpha.

A CYP450 &omega-oxidation metabolite of PGF2&alpha.

A glucocorticoid.

A glucocorticoid.

A glucocorticoid.

An endogenous agonist for LXR&alpha (EC₅₀ = 325 nM) that can induce the expression of the ABCA1 reverse cholesterol transporter to inhibit the overall absorption of cholesterol used as a substrate to monitor cholesterol transport or as

An endogenous agonist for LXR&alpha (EC₅₀ = 325 nM) that can induce the expression of the ABCA1 reverse cholesterol transporter to inhibit the overall absorption of cholesterol used as a substrate to monitor cholesterol transport or as

An endogenous agonist for LXR&alpha (EC₅₀ = 325 nM) that can induce the expression of the ABCA1 reverse cholesterol transporter to inhibit the overall absorption of cholesterol used as a substrate to monitor cholesterol transport or as

An analog of calcitriol that, like calcitriol, is a receptor-active form of vitamin D3 which effectively blocks PTH synthesis inhibits human keratinocyte proliferation and is beneficial in treating psoriasis blocks the proliferation while inducing

An analog of calcitriol that, like calcitriol, is a receptor-active form of vitamin D3 which effectively blocks PTH synthesis inhibits human keratinocyte proliferation and is beneficial in treating psoriasis blocks the proliferation while inducing