Biologically Active Small Molecules

A trichothecene mycotoxin that can be converted to DON in the body.

A trichothecene mycotoxin that can be converted to DON in the body.

An inhibitor of poly(ADP-ribose) polymerases (PARPs) (Ki = 1.8 &muM) has PARP-mediated actions in such diverse diseases as atherosclerosis, neurogenesis, and cancer.

An inhibitor of poly(ADP-ribose) polymerases (PARPs) (Ki = 1.8 &muM) has PARP-mediated actions in such diverse diseases as atherosclerosis, neurogenesis, and cancer.

A synthetic intermediate useful for pharmaceutical synthesis.

A synthetic intermediate useful for pharmaceutical synthesis.

A synthetic intermediate useful for pharmaceutical synthesis.

A synthetic intermediate useful for pharmaceutical synthesis.

A synthetic intermediate useful for pharmaceutical synthesis.

A synthetic intermediate useful for pharmaceutical synthesis.

A ribonucleotide reductase inhibitor and iron chelator with antitumor activity inhibits DNA synthesis and repair by destroying the tyrosine free radical in the R2/p53R2 subunits of ribonucleotide reductase through the formation of a redox active

A ribonucleotide reductase inhibitor and iron chelator with antitumor activity inhibits DNA synthesis and repair by destroying the tyrosine free radical in the R2/p53R2 subunits of ribonucleotide reductase through the formation of a redox active