Biologically Active Small Molecules

An inhibitor of SAH hydrolase depletes EZH2 levels and inhibits trimethylation of lysine 27 on histone H3 in acute myeloid leukemia cells in a dose-dependent manner (0.2-1 &muM) increases expression of the cell-cycle regulators p21, p27, and

An inhibitor of SAH hydrolase depletes EZH2 levels and inhibits trimethylation of lysine 27 on histone H3 in acute myeloid leukemia cells in a dose-dependent manner (0.2-1 &muM) increases expression of the cell-cycle regulators p21, p27, and

An inhibitor of SAH hydrolase depletes EZH2 levels and inhibits trimethylation of lysine 27 on histone H3 in acute myeloid leukemia cells in a dose-dependent manner (0.2-1 &muM) increases expression of the cell-cycle regulators p21, p27, and

A 1,2-dicarbonyl compound originating from the degradation of galactose can be formed by Maillard or caramelization reactions.

A 1,2-dicarbonyl compound originating from the degradation of galactose can be formed by Maillard or caramelization reactions.

A 1,2-dicarbonyl compound originating from the degradation of galactose can be formed by Maillard or caramelization reactions.

A highly reactive 2-oxoaldehyde intermediate of the Maillard reaction produced during oxidative stress in response to excess sugar consumption and in association with diabetes glycates and crosslinks proteins leading to the formation of advanced

A highly reactive 2-oxoaldehyde intermediate of the Maillard reaction produced during oxidative stress in response to excess sugar consumption and in association with diabetes glycates and crosslinks proteins leading to the formation of advanced

A highly reactive 2-oxoaldehyde intermediate of the Maillard reaction produced during oxidative stress in response to excess sugar consumption and in association with diabetes glycates and crosslinks proteins leading to the formation of advanced

A naturally occuring deaminated sialic acid that is thought to be a precursor for the biosynthesis of other members of the sialic acid family can be used to analyze nonulosonic acid residues in polysialoglycoproteins.

A naturally occuring deaminated sialic acid that is thought to be a precursor for the biosynthesis of other members of the sialic acid family can be used to analyze nonulosonic acid residues in polysialoglycoproteins.

A naturally occuring deaminated sialic acid that is thought to be a precursor for the biosynthesis of other members of the sialic acid family can be used to analyze nonulosonic acid residues in polysialoglycoproteins.