Biologically Active Small Molecules

A major adduct formed by the reaction of 4-HNE with GSH 4-HNE-GSH levels in liver, plasma, or isolated cells can serve as biomarkers for oxidative stress.

An internal standard for the quantification of 4-HNE-GSH (trifluoroacetate salt) by GC- or LC-MS.

An internal standard for the quantification of 4-HNE-GSH (trifluoroacetate salt) by GC- or LC-MS.

An internal standard for the quantification of 4-HNE-GSH (trifluoroacetate salt) by GC- or LC-MS.

An internal standard for the quantification of 4-HNE-GSH (trifluoroacetate salt) by GC- or LC-MS.

Peroxidation of common &omega-6 PUFAs such as linoleic acid, DGLA, and arachidonic acid can give rise to 4-HNE. 4-HNE is cleared rapidly from the plasma and undergoes enterohepatic circulation as a glutathione conjugate in the rat.

Peroxidation of common &omega-6 PUFAs such as linoleic acid, DGLA, and arachidonic acid can give rise to 4-HNE. 4-HNE is cleared rapidly from the plasma and undergoes enterohepatic circulation as a glutathione conjugate in the rat.

Peroxidation of common &omega-6 PUFAs such as linoleic acid, DGLA, and arachidonic acid can give rise to 4-HNE. 4-HNE is cleared rapidly from the plasma and undergoes enterohepatic circulation as a glutathione conjugate in the rat.

An internal standard for the quantification of 4-HNE mercapturic acid by GC- or LC-MS.

An internal standard for the quantification of 4-HNE mercapturic acid by GC- or LC-MS.

An internal standard for the quantification of 4-HNE mercapturic acid by GC- or LC-MS.

A lipid peroxidation product derived from oxidized &omega-6 PUFAs such as linoleic acid and arachidonic acid which is widely used as a marker of lipid peroxidation.