Biologically Active Small Molecules

5(S)-HpEPE is a monohydroperoxy PUFA produced by the action of 5-LO on EPA. It is metabolized to LTA5, a key intermediate in the formation of the 5-series leukotrienes. Alternatively, 5(S)-HpEPE is reduced to 5(S)-HEPE by peroxidases.

5(S)-HpEPE is a monohydroperoxy PUFA produced by the action of 5-LO on EPA. It is metabolized to LTA5, a key intermediate in the formation of the 5-series leukotrienes. Alternatively, 5(S)-HpEPE is reduced to 5(S)-HEPE by peroxidases.

A product of 5-LO catalyzed oxidation of arachidonic acid further metabolism by 5-LO gives LTA4, a key intermediate in the formation of the 4-series LTs.

A product of 5-LO catalyzed oxidation of arachidonic acid further metabolism by 5-LO gives LTA4, a key intermediate in the formation of the 4-series LTs.

A product of 5-LO catalyzed oxidation of arachidonic acid further metabolism by 5-LO gives LTA4, a key intermediate in the formation of the 4-series LTs.

A product of 5-LO catalyzed oxidation of arachidonic acid further metabolism by 5-LO gives LTA4, a key intermediate in the formation of the 4-series LTs.

5(Z),11(Z),14(Z)-Eicosatrienoic acid is a PUFA found in various natural sources including maritime pine (Pinus pinaster) seed oil (MPSO), gymnospermae leaves and seeds, and freshwater gastropods. A diet containing MPSO lowered HDL and ApoA1 levels

5(Z),11(Z),14(Z)-Eicosatrienoic acid is a PUFA found in various natural sources including maritime pine (Pinus pinaster) seed oil (MPSO), gymnospermae leaves and seeds, and freshwater gastropods. A diet containing MPSO lowered HDL and ApoA1 levels

5(Z),11(Z),14(Z)-Eicosatrienoic acid is a PUFA found in various natural sources including maritime pine (Pinus pinaster) seed oil (MPSO), gymnospermae leaves and seeds, and freshwater gastropods. A diet containing MPSO lowered HDL and ApoA1 levels

A novel &omega-6 C20:2 fatty acid.

A novel &omega-6 C20:2 fatty acid.

A novel &omega-6 C20:2 fatty acid.