Biologically Active Small Molecules

Inhibitor of p110a PI3K. It decreases viability of endometrial cancer cells and impairs glucose and insulin tolerance.

An irreversible inhibitor of TPPII commonly used at 10-100 &microM does not significantly interfere with the chymotrypsin-like activity of the proteasome also inhibits bleomycin hydrolase and puromycin-sensitive aminopeptidase when used at 50

An irreversible inhibitor of TPPII commonly used at 10-100 &microM does not significantly interfere with the chymotrypsin-like activity of the proteasome also inhibits bleomycin hydrolase and puromycin-sensitive aminopeptidase when used at 50

An irreversible inhibitor of TPPII commonly used at 10-100 &microM does not significantly interfere with the chymotrypsin-like activity of the proteasome also inhibits bleomycin hydrolase and puromycin-sensitive aminopeptidase when used at 50

A potent inhibitor of VEGF receptors, inhibiting VEGFR1, 2, and 3 with IC₅₀ values of 130, 23, and 18 nM, respectively orally bioavailable in vivo, blocking VEGF-induced angiogenesis and preventing the growth of primary tumors and

A potent inhibitor of VEGF receptors, inhibiting VEGFR1, 2, and 3 with IC₅₀ values of 130, 23, and 18 nM, respectively orally bioavailable in vivo, blocking VEGF-induced angiogenesis and preventing the growth of primary tumors and

A water-soluble azo compound used extensively as a free radical generator.

A water-soluble azo compound used extensively as a free radical generator.

An antiviral analog of guanosine, inhibiting the reverse transcriptase of HIV type 1 with an IC₅₀ value of 5.3 &muM blocks retroviral replication.

An antiviral analog of guanosine, inhibiting the reverse transcriptase of HIV type 1 with an IC₅₀ value of 5.3 &muM blocks retroviral replication.

An antiviral analog of guanosine, inhibiting the reverse transcriptase of HIV type 1 with an IC₅₀ value of 5.3 &muM blocks retroviral replication.

An antiviral analog of guanosine, inhibiting the reverse transcriptase of HIV type 1 with an IC₅₀ value of 5.3 &muM blocks retroviral replication.