Biologically Active Small Molecules

A fluorogenic substrate whose amino acids YVAD have been shown to be a preferred cleavage site for caspase-1 and -4.

A fluorogenic substrate whose amino acids YVAD have been shown to be a preferred cleavage site for caspase-1 and -4.

Ac-YVAD-CHO is a selective inhibitor of IL-1&beta converting enzyme (ICE Caspase-1). Caspase inhibitors interfere with the initiation of apoptosis and have numerous possible clinical applications.

Ac-YVAD-CHO is a selective inhibitor of IL-1&beta converting enzyme (ICE Caspase-1). Caspase inhibitors interfere with the initiation of apoptosis and have numerous possible clinical applications.

Ac-YVAD-CHO is a selective inhibitor of IL-1&beta converting enzyme (ICE Caspase-1). Caspase inhibitors interfere with the initiation of apoptosis and have numerous possible clinical applications.

A selective, irreversible inhibitor of IL-1b converting enzyme (ICE Caspase-1) neuroprotective in a rat model of cerebral ischemia.

A selective, irreversible inhibitor of IL-1b converting enzyme (ICE Caspase-1) neuroprotective in a rat model of cerebral ischemia.

A selective, irreversible inhibitor of IL-1b converting enzyme (ICE Caspase-1) neuroprotective in a rat model of cerebral ischemia.

A selective, irreversible inhibitor of IL-1b converting enzyme (ICE Caspase-1) neuroprotective in a rat model of cerebral ischemia.

A colorimetric substrate whose amino acids YVAD have been shown to be a preferred cleavage site for caspase-1 and -4.

A colorimetric substrate whose amino acids YVAD have been shown to be a preferred cleavage site for caspase-1 and -4.

A colorimetric substrate whose amino acids YVAD have been shown to be a preferred cleavage site for caspase-1 and -4.