Biologically Active Small Molecules

A selective inhibitor of PDGF receptor kinase with an IC50 value of20 &microM in human bone marrow inhibits the EGF receptor with an IC50 value of 820 &microM.

A selective inhibitor of PDGF receptor kinase with an IC50 value of20 &microM in human bone marrow inhibits the EGF receptor with an IC50 value of 820 &microM.

A selective inhibitor of PDGF receptor kinase with an IC50 value of20 &microM in human bone marrow inhibits the EGF receptor with an IC50 value of 820 &microM.

An selective inhibitor of JAK2 activity that blocks leukemic cell growth in vitro and in vivo by inducing programmed cell death blocks growth of all pre-B acute leukemia cells at a concentration of 5 &microM.

An selective inhibitor of JAK2 activity that blocks leukemic cell growth in vitro and in vivo by inducing programmed cell death blocks growth of all pre-B acute leukemia cells at a concentration of 5 &microM.

An selective inhibitor of JAK2 activity that blocks leukemic cell growth in vitro and in vivo by inducing programmed cell death blocks growth of all pre-B acute leukemia cells at a concentration of 5 &microM.

An selective inhibitor of JAK2 activity that blocks leukemic cell growth in vitro and in vivo by inducing programmed cell death blocks growth of all pre-B acute leukemia cells at a concentration of 5 &microM.

An inhibitor of EGF receptor kinase with an IC50 value of 1 &microM in HT-22 cells.

An inhibitor of EGF receptor kinase with an IC50 value of 1 &microM in HT-22 cells.

An inhibitor of EGF receptor kinase with an IC50 value of 1 &microM in HT-22 cells.

An inhibitor of EGF receptor kinase with an IC50 value of 1 &microM in HT-22 cells.

An inhibitor of EGF receptor kinase with an IC50 value of 3 &microM in the human epidermoid carcinoma cell line A431.