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10010313-25AG-99 is an inhibitor of EGF receptor kinase with an IC50 value of 10 µM in the human epidermoid carcinoma cell line A431.
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10010313-5AG-99 is an inhibitor of EGF receptor kinase with an IC50 value of 10 µM in the human epidermoid carcinoma cell line A431.
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10010313-50AG-99 is an inhibitor of EGF receptor kinase with an IC50 value of 10 µM in the human epidermoid carcinoma cell line A431.
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17259-1A tyrphostin that targets transforming Bcr-Abl fusion proteins (p185Bcr-Abl, p210Bcr-Abl, as well as normal c-Abl (IC<sub>50</sub>s = 4.3, 1, and 7.1 µM, respectively, for human proteins) also inhibits EGFR (IC<sub>50</sub> = 0.25 µM).
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17259-10A tyrphostin that targets transforming Bcr-Abl fusion proteins (p185Bcr-Abl, p210Bcr-Abl, as well as normal c-Abl (IC<sub>50</sub>s = 4.3, 1, and 7.1 µM, respectively, for human proteins) also inhibits EGFR (IC<sub>50</sub> = 0.25 µM).
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17259-5A tyrphostin that targets transforming Bcr-Abl fusion proteins (p185Bcr-Abl, p210Bcr-Abl, as well as normal c-Abl (IC<sub>50</sub>s = 4.3, 1, and 7.1 µM, respectively, for human proteins) also inhibits EGFR (IC<sub>50</sub> = 0.25 µM).
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14624-1Selective inhibitor of IDH1 R132H and R132C mutants in vitro (IC<sub>50</sub>s = 0.07 and 0.
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14624-10Selective inhibitor of IDH1 R132H and R132C mutants in vitro (IC<sub>50</sub>s = 0.07 and 0.
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14624-25Selective inhibitor of IDH1 R132H and R132C mutants in vitro (IC<sub>50</sub>s = 0.07 and 0.
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14624-5Selective inhibitor of IDH1 R132H and R132C mutants in vitro (IC<sub>50</sub>s = 0.07 and 0.
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14639-1A potent, selective inhibitor of mutant IDH2 (IC<sub>50</sub> = 23 nM) that inhibits 2-HG formation in human glioblastoma U87 and TF-1 cells expressing IDH2-R140Q (IC<sub>50</sub>s = 11 and 18 nM, respectively) suppresses cell growth of primary
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14639-10A potent, selective inhibitor of mutant IDH2 (IC<sub>50</sub> = 23 nM) that inhibits 2-HG formation in human glioblastoma U87 and TF-1 cells expressing IDH2-R140Q (IC<sub>50</sub>s = 11 and 18 nM, respectively) suppresses cell growth of primary