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10011546-50A potent 5-HT2 receptor agonist with ocular hypotensive activity binds to the human and rat 5-HT2 receptors in cerebral cortex homogenates with IC50 values of 1.5 and 0.
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13620-1The isopropyl ester prodrug of AL 6556, a PGD2 receptor agonist (Ki = 3.2 µM, EC50 = 0.80 µM) produces a maximum 53% drop in IOP of the ocular hypertensive monkey with a 1 µg dose given twice daily.
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13620-10The isopropyl ester prodrug of AL 6556, a PGD2 receptor agonist (Ki = 3.2 µM, EC50 = 0.80 µM) produces a maximum 53% drop in IOP of the ocular hypertensive monkey with a 1 µg dose given twice daily.
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13620-5The isopropyl ester prodrug of AL 6556, a PGD2 receptor agonist (Ki = 3.2 µM, EC50 = 0.80 µM) produces a maximum 53% drop in IOP of the ocular hypertensive monkey with a 1 µg dose given twice daily.
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13620-500The isopropyl ester prodrug of AL 6556, a PGD2 receptor agonist (Ki = 3.2 µM, EC50 = 0.80 µM) produces a maximum 53% drop in IOP of the ocular hypertensive monkey with a 1 µg dose given twice daily.
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10010470-1An analog of AL 8810 in which the C-1 carboxyl group has been modified to an N-ethyl amide analogous to Bimatoprost.
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10010470-10An analog of AL 8810 in which the C-1 carboxyl group has been modified to an N-ethyl amide analogous to Bimatoprost.
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10010470-5An analog of AL 8810 in which the C-1 carboxyl group has been modified to an N-ethyl amide analogous to Bimatoprost.
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10113-1A lipid soluble, esterified prodrug of AL 8810.
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10113-10A lipid soluble, esterified prodrug of AL 8810.
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10113-5A lipid soluble, esterified prodrug of AL 8810.
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10008370-1AL 8810 methyl ester is a lipid soluble, esterified prodrug form of AL 8810 analogous to the commonly used therapeutic intraocular PG compounds such as latanoprost and travoprost. The pharmacology of AL 8810 methyl ester has not been published.