Biologically Active Small Molecules

A fungal metabolite that inhibits DGAT activity, preventing triacylglycerol formation (IC₅₀s = 10.2 and 15.5 &microM in rat liver microsomes and Raji cells, respectively.

A fungal metabolite that inhibits DGAT activity, preventing triacylglycerol formation (IC₅₀s = 17.5 and 2.8 &microM in rat liver microsomes and Raji cells, respectively).

A fungal metabolite that inhibits DGAT activity, preventing triacylglycerol formation (IC₅₀s = 17.5 and 2.8 &microM in rat liver microsomes and Raji cells, respectively).

A prodrug that through dephosphorylation by alkaline phosphatase is converted to an active thiol, WR 1065 that has free radical scavenging, DNA protective, and hypoxia inducing activities used to selectively reduce toxicity in normal tissues

A prodrug that through dephosphorylation by alkaline phosphatase is converted to an active thiol, WR 1065 that has free radical scavenging, DNA protective, and hypoxia inducing activities used to selectively reduce toxicity in normal tissues

A prodrug that through dephosphorylation by alkaline phosphatase is converted to an active thiol, WR 1065 that has free radical scavenging, DNA protective, and hypoxia inducing activities used to selectively reduce toxicity in normal tissues

An aminoglycoside antibiotic derived from kanamycin A.

An aminoglycoside antibiotic derived from kanamycin A.

A potassium-sparing diuretic that promotes the loss of sodium and water from the body by directly blocking epithelial sodium channels (ENaCs) also blocks Na+/H+ exchangers (NHE-1) in the heart and acid-sensing ion channels (ASICs), which are

A potassium-sparing diuretic that promotes the loss of sodium and water from the body by directly blocking epithelial sodium channels (ENaCs) also blocks Na+/H+ exchangers (NHE-1) in the heart and acid-sensing ion channels (ASICs), which are

L-Alaninol is an amino acid alcohol that exhibits anticancer activity. L-Alaninol inhibits proliferation of melanoma cells and increases levels of cytochrome c reductase and tau-glutamyl transpeptidase. Grade: &ge98%

L-Alaninol is an amino acid alcohol that exhibits anticancer activity. L-Alaninol inhibits proliferation of melanoma cells and increases levels of cytochrome c reductase and tau-glutamyl transpeptidase. Grade: &ge98%