-
10004176-50Promotes the cytochrome c-dependent oligomerization of Apaf-1 into the mature apoptosome, thus increasing procaspase-9 processing and subsequent caspase-3 activation induces apoptosis in leukemia cells (IC50 = 4-9 &muM)
-
A5353-100 TestsThis product is used to measure apoptosis in vitro.
-
17675-10An inhibitor of Hsp70 (65% inhibition at 200 µM) that acts by blocking its ATPase activity induces apoptosis in cancer cells (IC<sub>50</sub> = 5-7 µM) prevents the growth of A549, RKO, and HeLa cell xenografts in mice without
-
17675-25An inhibitor of Hsp70 (65% inhibition at 200 µM) that acts by blocking its ATPase activity induces apoptosis in cancer cells (IC<sub>50</sub> = 5-7 µM) prevents the growth of A549, RKO, and HeLa cell xenografts in mice without
-
17675-5An inhibitor of Hsp70 (65% inhibition at 200 µM) that acts by blocking its ATPase activity induces apoptosis in cancer cells (IC<sub>50</sub> = 5-7 µM) prevents the growth of A549, RKO, and HeLa cell xenografts in mice without
-
17675-50An inhibitor of Hsp70 (65% inhibition at 200 µM) that acts by blocking its ATPase activity induces apoptosis in cancer cells (IC<sub>50</sub> = 5-7 µM) prevents the growth of A549, RKO, and HeLa cell xenografts in mice without
-
18502-1An orally active inhibitor of PDE4 with an IC<sub>50</sub> value of 74 nM when tested in U937 cell lysates with 1 mM cAMP decreases epidermal thickness in a mouse model of psoriasis, reduces both TNF-&alpha and MMP-3 production in gut cells from
-
18502-10An orally active inhibitor of PDE4 with an IC<sub>50</sub> value of 74 nM when tested in U937 cell lysates with 1 mM cAMP decreases epidermal thickness in a mouse model of psoriasis, reduces both TNF-&alpha and MMP-3 production in gut cells from
-
18502-25An orally active inhibitor of PDE4 with an IC<sub>50</sub> value of 74 nM when tested in U937 cell lysates with 1 mM cAMP decreases epidermal thickness in a mouse model of psoriasis, reduces both TNF-&alpha and MMP-3 production in gut cells from
-
18502-5An orally active inhibitor of PDE4 with an IC<sub>50</sub> value of 74 nM when tested in U937 cell lysates with 1 mM cAMP decreases epidermal thickness in a mouse model of psoriasis, reduces both TNF-&alpha and MMP-3 production in gut cells from
-
14867-1An antiemetic compound that selectively antagonizes the human NK1 receptor (Kis = 3 and 454.1 nM for hNK1 and hNK3, respectively IC<sub>50</sub> = 0.09 nM for hNK1).
-
14867-10An antiemetic compound that selectively antagonizes the human NK1 receptor (Kis = 3 and 454.1 nM for hNK1 and hNK3, respectively IC<sub>50</sub> = 0.09 nM for hNK1).